Home, sweet home: how mucus accommodates our microbiota.
Home, sweet home: how mucus accommodates our microbiota.
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DOI:
10.1111/febs.15504
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发表时间:
2021-03
期刊:
影响因子:
--
通讯作者:
Ribbeck K
中科院分区:
文献类型:
--
作者:
Wang BX;Wu CM;Ribbeck K
As a natural environment for human-microbiota interactions, healthy mucus houses a remarkably stable and diverse microbial community. Maintaining this microbiota is essential to human health, both to support the commensal bacteria that perform a wide array of beneficial functions and to prevent the outgrowth of pathogens. However, how the host selects and maintains a specialized microbiota remains largely unknown. In this viewpoint, we propose several strategies by which mucus may regulate the composition and function of the human microbiota and discuss how compromised mucus barriers in disease can give rise to microbial dysbiosis.
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