Urinary Sodium-to-Potassium Ratio Tracks the Changes in Salt Intake during an Experimental Feeding Study Using Standardized Low-Salt and High-Salt Meals among Healthy Japanese Volunteers.

Urinary Sodium-to-Potassium Ratio Tracks the Changes in Salt Intake during an Experimental Feeding Study Using Standardized Low-Salt and High-Salt Meals among Healthy Japanese Volunteers.
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DOI:
10.3390/nu9090951
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发表时间:
2017-08-29
期刊:
影响因子:
5.9
通讯作者:
Yatabe J
Yatabe J
中科院分区:
医学2区
文献类型:
--
作者:
Yatabe MS;Iwahori T;Watanabe A;Takano K;Sanada H;Watanabe T;Ichihara A;Felder RA;Miura K;Ueshima H;Kimura J;Yatabe J

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钠/钾比率被认为是一个有用的指数,监测它可以有效地减少钠和增加钾,因为实用的方法(自我监测设备和可靠的个人估计从现场尿)可用于评估这些水平的个人。一项降低Na/K比值的干预试验表明,Na/K比值的降低主要涉及Na的减少,K的变化很小。本研究的目的是澄清饮食钠摄入量和尿钠/钾摩尔比之间的关系,使用标准化的低盐和高盐饮食,与相同的饮食钾摄入量,以确定相应的钠/钾比。14名健康的年轻成年志愿者分别摄入低盐(每天3克盐)和高盐(每天20克盐)膳食7天。使用便携式尿Na/K计,参与者在每次排尿时测量他们的现场尿,并在每个饮食期的最后一天收集24小时尿。在无限制、低盐和高盐饮食期的最后一天,24小时尿Na/K比的组平均值分别为4.2、1.0和6.9,而每日平均点尿Na/K比的组平均值分别为4.2、1.1和6.6。尿Na/K比值跟踪饮食盐摄入量的变化,并在每次饮食变化后约3天达到平台期。经常监测现场尿钠/钾比值可能有助于个人坚持适当的饮食钠摄入量。
The Na/K ratio is considered to be a useful index, the monitoring of which allows an effective Na reduction and K increase, because practical methods (self-monitoring devices and reliable individual estimates from spot urine) are available for assessing these levels in individuals. An intervention trial for lowering the Na/K ratio has demonstrated that a reduction of the Na/K ratio mainly involved Na reduction, with only a small change in K. The present study aimed to clarify the relationship between dietary Na intake and the urinary Na/K molar ratio, using standardized low- and high-salt diets, with an equal dietary K intake, to determine the corresponding Na/K ratio. Fourteen healthy young adult volunteers ingested low-salt (3 g salt per day) and high-salt (20 g salt per day) meals for seven days each. Using a portable urinary Na/K meter, participants measured their spot urine at each voiding, and 24-h urine was collected on the last day of each diet period. On the last day of the unrestricted, low-salt, and high-salt diet periods, the group averages of the 24-h urine Na/K ratio were 4.2, 1.0, and 6.9, while the group averages of the daily mean spot urine Na/K ratio were 4.2, 1.1, and 6.6, respectively. The urinary Na/K ratio tracked changes in dietary salt intake, and reached a plateau approximately three days after each change in diet. Frequent monitoring of the spot urine Na/K ratio may help individuals adhere to an appropriate dietary Na intake.
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