Coronary artery spasm: review and update.
Coronary artery spasm: review and update.
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DOI:
10.7150/ijms.9623
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发表时间:
2014
影响因子:
3.6
通讯作者:
Hung MY
中科院分区:
文献类型:
--
作者:
Hung MJ;Hu P;Hung MY
Coronary artery spasm (CAS), an intense vasoconstriction of coronary arteries that causes total or subtotal vessel occlusion, plays an important role in myocardial ischemic syndromes including stable and unstable angina, acute myocardial infarction, and sudden cardiac death. Coronary angiography and provocative testing usually is required to establish a definitive diagnosis. While the mechanisms underlying the development of CAS are still poorly understood, CAS appears to be a multifactorial disease but is not associated with the traditional risk factors for coronary artery disease. The diagnosis of CAS has important therapeutic implications, as calcium antagonists, not β-blockers, are the cornerstone of medical treatment. The prognosis is generally considered benign; however, recurrent episodes of angina are frequently observed. We provide a review of the literature and summarize the current state of knowledge regarding the pathogenesis of CAS.
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影响因子:
37.8
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通讯作者:
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