The multifunctional nature of mitochondrial contact site proteins.
The multifunctional nature of mitochondrial contact site proteins.
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DOI:
10.1016/j.ceb.2020.02.010
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发表时间:
2020-08
影响因子:
7.5
通讯作者:
Lackner LL
中科院分区:
文献类型:
--
作者:
Harper CS;White AJ;Lackner LL
Mitochondria make physical contact with nearly every other membrane in the cell, and these contacts have a rich variety of functions that are carried out by proteins that reside at the sites of contact. Over the past decade, tremendous insight into the identity and functions of proteins localized to mitochondria contact sites has been gained. In doing so, it has become clear that one protein or protein complex can contribute to contact site formation and function in a wide variety of ways. Thus, complex and often surprising relationships between the roles of a mitochondria contact site and its multifunctional resident proteins continue to be unraveled.
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