Impaired implicit learning in schizophrenia.
Impaired implicit learning in schizophrenia.
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DOI：
10.1037/a0012602
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发表时间：
2008-09
期刊：
影响因子：
2.4
通讯作者：
Nuechterlein, Keith H.
中科院分区：
文献类型：
--
作者：
Horan, William P.;Green, Michael F.;Knowlton, Barbara J.;Wynn, Jonathan K.;Mintz, Jim;Nuechterlein, Keith H.
精神分裂症患者始终表现出外显学习和记忆任务的缺陷。相比之下，他们在内隐处理任务上的表现往往相对完整，尽管大多数研究都集中在运动技能的内隐学习上。本研究使用两种不同的认知技能任务评估了59名精神分裂症门诊患者和43名健康对照者的内隐学习。参与者完成了评估程序性习惯学习的概率分类任务和评估复杂规则知识附带学习的人工语法任务，以及显性语言学习和记忆任务。除了在显性学习任务上的表现比对照组差之外，患者在概率分类任务上的整体表现也更差，这涉及到通过逐个试验的表现反馈来逐步学习。然而，患者和对照组在人工语法任务中表现出相似的学习水平，这表明在缺乏表现反馈的情况下，他们仍保留了获得复杂规则知识的能力。讨论了精神分裂症患者概率分类任务表现不佳的可能解释。
Schizophrenia patients consistently show deficits on tasks of explicit learning and memory. In contrast, their performance on implicit processing tasks often appears to be relatively intact, though most studies have focused on implicit learning of motor skills. This study evaluated implicit learning in 59 medicated schizophrenia outpatients and 43 healthy controls using two different cognitive skill tasks. Participants completed a Probabilistic Classification task to assess procedural habit learning and an Artificial Grammar task to assess incidental learning of complex rule-based knowledge, as well as an explicit verbal learning and memory task. In addition to performing worse than controls on the explicit learning task, patients showed worse overall performance on the Probabilistic Classification task, which involves gradual learning through trial-by-trial performance feedback. However, patients and controls showed similar levels of learning on the Artificial Grammar task, suggesting a preserved ability to acquire complex rule-based knowledge in the absence of performance feedback. Discussion focuses on possible explanations for schizophrenia patients’ poor Probabilistic Classification task performance.
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影响因子：
1.7
作者：
Green, M F;Kern, R S;Kee, K
通讯作者：
Kee, K
DOI：
10.1037/0278-7393.30.3.714
发表时间：
2004-05-01
影响因子：
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作者：
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DOI：
10.1111/j.0963-7214.2006.00395.x
发表时间：
2006-02-01
影响因子：
7.2
作者：
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通讯作者：
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影响因子：
3.9
作者：
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通讯作者：
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