Behavioral sensitization is greater after repeated versus single chronic cocaine dosing regimens.
Behavioral sensitization is greater after repeated versus single chronic cocaine dosing regimens.
复制标题
与单次慢性可卡因给药方案相比，重复给药后的行为过敏程度更高。
DOI：
10.1016/s0014-2999(02)01437-1
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发表时间：
2002
影响因子：
5
通讯作者：
Ellinwood,EverettH
中科院分区：
文献类型：
--
作者：
Davidson,Colin;Lazarus,Cindy;Lee,TongH;Ellinwood,EverettH
Cocaine dosing regimens in animals are used to model behavioral and neurochemical changes in human cocaine abusers. Typically, rats are dosed for 5–14 days and assessed at some point during withdrawal. However, human cocaine bingers undergo multiple periods of several days of abuse. Here, we model the human binge pattern by giving rats two separate cocaine dosing regimens which results in greater behavioral sensitization than a single cocaine dosing regimen. This model also allows for the testing of drugs in reversal of a previously established sensitization. Multiple cocaine regimens may thus provide a better model for the human condition.
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影响因子：
7.6
作者：
F. J. White;Amit Joshi;Timothy E. Koeltzow;Xiu-Ti Hu
通讯作者：
F. J. White;Amit Joshi;Timothy E. Koeltzow;Xiu-Ti Hu
影响因子：
56.9
作者：
ANTELMAN, SM;EICHLER, AJ;KOCAN, D
通讯作者：
KOCAN, D
对兴奋剂引起的异常行为的逆转耐受性。
DOI：
--
发表时间：
1977
期刊：
Life Science
影响因子：
--
作者：
M. Kilbey;E. Ellinwood
通讯作者：
E. Ellinwood
影响因子：
5
作者：
ELLINWOOD, EH;BALSTER, RL
通讯作者：
BALSTER, RL
间歇性和连续性可卡因给药：戒断期间的残余行为状态
影响因子：
3.6
作者：
G. King;C. Joyner;T. Lee;Cynthia M. Kuhn;E. Ellinwood
通讯作者：
E. Ellinwood