Super-resolution ultrasound imaging method for microvasculature in vivo with a high temporal accuracy.
Super-resolution ultrasound imaging method for microvasculature in vivo with a high temporal accuracy.
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DOI：
10.1038/s41598-018-32235-2
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发表时间：
2018-09-17
影响因子：
4.6
通讯作者：
Kim K
中科院分区：
文献类型：
--
作者：
Yu J;Lavery L;Kim K
Traditional ultrasound imaging techniques are limited in spatial resolution to visualize angiogenic vasa vasorum that is considered as an important marker for atherosclerotic plaque progression and vulnerability. The recently introduced super-resolution imaging technique based on microbubble center localization has shown potential to achieve unprecedented high spatial resolution beyond the acoustic diffraction limit. However, a major drawback of the current super-resolution imaging approach is low temporal resolution because it requires a large number of imaging frames. In this study, a new imaging sequence and signal processing approach for super-resolution ultrasound imaging are presented to improve temporal resolution by employing deconvolution and spatio-temporal-interframe-correlation based data acquisition. In vivo feasibility of the developed technology is demonstrated and evaluated in imaging vasa vasorum in the rabbit atherosclerosis model. The proposed method not only identifies a tiny vessel with a diameter of 41 μm, 5 times higher spatial resolution than the acoustic diffraction limit at 7.7 MHz, but also significantly improves temporal resolution that allows for imaging vessels over cardiac motion.
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影响因子：
14
作者：
Lee, Sang Chol;Carr, Chad L.;Davidson, Brian P.;Ellegala, Dilantha;Xie, Aris;Ammi, Azzdine;Belcik, Todd;Lindner, Jonathan R.
通讯作者：
Lindner, Jonathan R.
使用第三个谐波的35 MHz/105 MHz双元素聚焦换能器用于血管内超声组织成像。
DOI：
10.3390/s18072290
发表时间：
2018-07-15
期刊：
Sensors (Basel, Switzerland)
影响因子：
--
作者：
Lee J;Moon JY;Chang JH
通讯作者：
Chang JH
影响因子：
10.6
作者：
Demene, Charlie;Deffieux, Thomas;Tanter, Mickael
通讯作者：
Tanter, Mickael
DOI：
10.1152/ajpheart.00399.2003
发表时间：
2003-11-01
影响因子：
4.8
作者：
Gössl, M;Malyar, NM;Ritman, EL
通讯作者：
Ritman, EL
影响因子：
3.8
作者：
Huang, Chih-Chung;Chen, Pei-Yu;Lee, Po-Yang
通讯作者：
Lee, Po-Yang