Depression as a risk factor for mortality in individuals with diabetes: a meta-analysis of prospective studies.
Depression as a risk factor for mortality in individuals with diabetes: a meta-analysis of prospective studies.
复制标题
DOI：
10.1371/journal.pone.0079809
复制
发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Kruse J
中科院分区：
文献类型：
--
作者：
Hofmann M;Köhler B;Leichsenring F;Kruse J
量化通过自我报告测量的抑郁症和通过临床访谈测量的抑郁症对糖尿病患者全因死亡率的影响，并分析两种关联的强度，协变量的影响以及评估自评抑郁症状的研究与使用临床访谈测量抑郁症作为死亡率预测因子的研究之间的可能差异。PUBMED和PsycINFO检索了截至2013年7月的前瞻性研究，评估抑郁症，糖尿病和死亡率。使用随机效应模型计算合并风险比。16项研究符合纳入标准。在调整人口统计学变量后，通过自我报告测量的抑郁症与全因死亡风险增加相关（合并HR = 2.56，95% CI 1.89-3.47），在额外调整糖尿病并发症后，死亡风险仍然很高（HR = 1.76，95% CI 1.45-2.14）。 6项研究报告了通过临床访谈测量的抑郁症校正HR，支持其他模型的结果（HR = 1.49，95% CI 1.15-1.93）。 通过自我报告测量的抑郁症和通过临床访谈测量的抑郁症都对糖尿病患者的死亡率产生不利影响。然而，结果受到主要研究异质性的限制。目前尚不清楚自我报告或抑郁症的临床访谈是否是更准确的预测因素。
To quantify the impact of depression measured by self-reports and depression measured by clinical interview on all-cause mortality in individuals with diabetes and to analyze the strength of both associations, the influence of covariates, and possible differences between studies assessing self-rated depressive symptoms and those using a clinical interview to measure depression as predictors of mortality. PUBMED and PsycINFO were searched up to July 2013 for prospective studies assessing depression, diabetes and mortality. The pooled hazard ratios were calculated using random-effects models. Sixteen studies met the inclusion criteria. After adjustment for demographic variables depression measured by self-reports was associated with an increased all-cause mortality risk (pooled HR = 2.56, 95% CI 1.89–3.47), and the mortality risk remained high after additional adjustment for diabetes complications (HR = 1.76, 95% CI 1.45–2.14,). Six studies reporting adjusted HRs for depression measured by clinical interviews supported the results of the other models (HR = 1.49, 95% CI 1.15–1.93). Both depression measured by self-report and depression measured by clinical interview have an unfavorable impact on mortality in individuals with diabetes. The results, however, are limited by the heterogeneity of the primary studies. It remains unclear whether self-reports or clinical interviews for depression are the more precise predictor.
登录
查看更多内容
影响因子：
--
作者：
Pan, An;Lucas, Michel;Sun, Qi;van Dam, Rob M.;Franco, Oscar H.;Willett, Walter C.;Manson, JoAnn E.;Rexrode, Kathryn M.;Ascherio, Alberto;Hu, Frank B.
通讯作者：
Hu, Frank B.
影响因子：
16.2
作者：
Katon, WJ;Rutter, C;Von Korff, M
通讯作者：
Von Korff, M
影响因子：
16.2
作者：
Egede, LE;Nietert, PJ;Zheng, D
通讯作者：
Zheng, D
影响因子：
8.2
作者：
Ahola, A. J.;Harjutsalo, V.;Groop, P. -H.
通讯作者：
Groop, P. -H.
影响因子：
7
作者：
Park M;Katon WJ;Wolf FM
通讯作者：
Wolf FM