How challenges in auditory fMRI led to general advancements for the field.
How challenges in auditory fMRI led to general advancements for the field.
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DOI：
10.1016/j.neuroimage.2012.01.006
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发表时间：
2012-08-15
期刊：
影响因子：
5.7
通讯作者：
Hall, Deborah A.
中科院分区：
文献类型：
--
作者：
Talavage, Thomas M.;Hall, Deborah A.
在功能磁共振研究的早期，听神经科学界试图扩大其对听力潜在生理学的知识，同时也试图了解在功能磁共振环境中工作的固有声学劣势。著名的听觉研究实验室和著名的功能磁共振成像中心之间的早期合作努力导致了一些关键技术进步的发展，这些技术进步随后被广泛用于阐明听觉神经生理学的原理。也许关键的成像进步是同时和并行地开发使用脉冲序列的策略，在脉冲序列中体积采集是“聚集的”，提供了在没有直接掩蔽的情况下可以呈现刺激的间隙。这样的序列在使用听觉刺激的功能磁共振研究中已经变得普遍，在一系列翻译研究领域也是如此。这篇综述介绍了导致这些序列的人和听觉神经生理学研究的平行故事。
In the early years of fMRI research, the auditory neuroscience community sought to expand its knowledge of the underlying physiology of hearing, while also seeking to come to grips with the inherent acoustic disadvantages of working in the fMRI environment. Early collaborative efforts between prominent auditory research laboratories and prominent fMRI centers led to development of a number of key technical advances that have subsequently been widely used to elucidate principles of auditory neurophysiology. Perhaps the key imaging advance was the simultaneous and parallel development of strategies to use pulse sequences in which the volume acquisitions were “clustered,” providing gaps in which stimuli could be presented without direct masking. Such sequences have become widespread in fMRI studies using auditory stimuli and also in a range of translational research domains. This review presents the parallel stories of the people and the auditory neurophysiology research that led to these sequences.
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