Tonotopic organization of human auditory cortex.

Tonotopic organization of human auditory cortex.
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DOI:
10.1016/j.neuroimage.2010.01.046
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发表时间:
2010-04-15
期刊:
影响因子:
5.7
通讯作者:
Binder, Jeffrey R.
Binder, Jeffrey R.
中科院分区:
医学1区
文献类型:
--
作者:
Humphries, Colin;Liebenthal, Einat;Binder, Jeffrey R.

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利用功能磁共振成像技术研究了人类听觉皮层的音调场结构。受试者在六个不同的频带中随机交替多音序列,集中在200,400,800,1600,3200和6400 Hz。两个镜像对称的频率梯度被发现延伸沿着一个前-后轴从一个区域上的外侧Heschl的回(HG),这优先响应于较低的频率,对区域后方和前方的HG是敏感的较高的频率。因此,这两个主梯度的取向大致垂直于HG,而不是如先前假设的平行。在上级颞回的外侧后方观察到第三个较小的梯度。结果表明,人类和非人灵长类动物的听觉皮层的音调组织之间的密切同源性。
The organization of tonotopic fields in human auditory cortex was investigated using functional magnetic resonance imaging. Subjects were presented with stochastically alternating multi-tone sequences in six different frequency bands, centered at 200, 400, 800, 1600, 3200, and 6400 Hz. Two mirror-symmetric frequency gradients were found extending along an anterior-posterior axis from a zone on the lateral aspect of Heschl's gyrus (HG), which responds preferentially to lower frequencies, toward zones posterior and anterior to HG that are sensitive to higher frequencies. The orientation of these two principal gradients is thus roughly perpendicular to HG, rather than parallel as previously assumed. A third, smaller gradient was observed in the lateral posterior aspect of the superior temporal gyrus. The results suggest close homologies between the tonotopic organization of human and nonhuman primate auditory cortex.
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