Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue - a review.
Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue - a review.
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DOI：
10.1186/s13000-014-0221-9
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发表时间：
2014-11-29
影响因子：
2.6
通讯作者：
Reifenrath J
中科院分区：
文献类型：
--
作者：
Fedchenko N;Reifenrath J
免疫组织化学（IHC）是一种在医学科学的临床和实验部分都得到广泛认可的方法。它允许接收关于任何组织中的任何过程的有价值的信息，特别是在骨骼中。每年，IHC接收的数据量以几何级数增长。但是，缺乏标准化，特别是在分析后阶段（结果的解释和报告），使得不同研究的结果无法进行比较。使用检索词“免疫组织化学”和“评分系统”进行了综合PubMED文献检索，识别出773篇描述IHC结果的文章。在进一步的人工分析后，选择了120篇文章对所用方法进行详细评价。确定、分析和描述了解释和呈现IHC分析结果的六种主要方法。文章中提供的IHC数据评价和解释的现有方法的概述可用于骨组织研究，并可用于更好地理解现有评分系统或开发新的评分系统。标准的多参数、半定量IHC评分系统应简化并澄清对收到的数据进行解释和报告的过程。本文的虚拟幻灯片可以在这里找到：http://www.diagnosticpathology.diagnomx.eu/vs/13000_2014_221
Immunohistochemistry (IHC) is a well-established, widely accepted method in both clinical and experimental parts of medical science. It allows receiving valuable information about any process in any tissue, and especially in bone. Each year the amount of data, received by IHC, grows in geometric progression. But the lack of standardization, especially on the post-analytical stage (interpreting and reporting of results), makes the comparison of the results of different studies impossible. Comprehensive PubMED literature search with a combination of search words “immunohistochemistry” and “scoring system” was performed and 773 articles describing IHC results were identified. After further manual analysis 120 articles were selected for detailed evaluation of used approaches. Six major approaches to the interpretation and presentation of IHC analysis results were identified, analyzed and described. The overview of the existing approaches in evaluation and interpretation of IHC data, which are provided in the article, can be used in bone tissue research and for either better understanding of existing scoring systems or developing a new one. Standard multiparametric, semiquantitative IHC scoring systems should simplify and clarify the process of interpretation and reporting of received data. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/13000_2014_221
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DOI：
10.1186/bcr3600
发表时间：
2014-01-22
期刊：
Breast cancer research : BCR
影响因子：
--
作者：
Bramwell VH;Tuck AB;Chapman JA;Anborgh PH;Postenka CO;Al-Katib W;Shepherd LE;Han L;Wilson CF;Pritchard KI;Pollak MN;Chambers AF
通讯作者：
Chambers AF
影响因子：
4.9
作者：
Bondarenko, A.;Angrisani, N.;Reifenrath, J.
通讯作者：
Reifenrath, J.
影响因子：
14
作者：
Cao, Lingyan;Wang, Jing;Liu, Changsheng
通讯作者：
Liu, Changsheng
DOI：
10.2310/7070.2002.34305
发表时间：
2002-10-01
期刊：
JOURNAL OF OTOLARYNGOLOGY
影响因子：
--
作者：
Campisi, P;Hamdy, RC;Lessard, ML
通讯作者：
Lessard, ML
影响因子：
8.8
作者：
Ali, H. R.;Irwin, M.;Morris, L.;Dawson, S-J;Blows, F. M.;Provenzano, E.;Mahler-Araujo, B.;Pharoah, P. D.;Walton, N. A.;Brenton, J. D.;Caldas, C.
通讯作者：
Caldas, C.