Effects of orientation-dependent susceptibility on MR chemical shift brain thermometry.
Effects of orientation-dependent susceptibility on MR chemical shift brain thermometry.
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DOI：
10.1016/j.mri.2022.10.007
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发表时间：
2023-01
影响因子：
2.5
通讯作者：
Fleischer, Candace C.
中科院分区：
文献类型：
--
作者：
Wang, Kelly J.;Sung, Dongsuk;Risk, Benjamin B.;Allen, Jason W.;Fleischer, Candace C.
关键词：
磁共振化学位移测温法（CST）中存在的取向依赖性磁化率伪影会影响精确的温度计算。在这里，我们量化的影响，白色物质（WM）道的方向CST由于组织特异性的易感性。29名健康志愿者（27±4岁）在3 T MR扫描仪上使用32通道头部线圈进行扫描。获得用于CST的扩散张量成像（DTI）、T1加权成像和单体素光谱（SVS）。然后要求参与者旋转他们的头部~3 - 5°（偏航或滚动）以改变WM束相对于外部磁场的方向。头部旋转后，进行第二次SVS扫描和T1加权成像。WM分数归一化的DTI主特征向量（V1）图像用于计算V1的x-y分量的长度，其用作垂直于B 0的WM束的替代。线性回归模型被用来确定垂直WM束和脑温度之间的关系。头部旋转扫描后和扫描前的脑部温度（−0.72 °C ± 1.36 °C，p = 0.01）存在显著差异，但体温（0.012 °C ± 0.07 °C，p = 0.37）无显著差异。头部旋转后，大脑温度的差异与垂直WM束的相应变化呈正相关（R2 = 0.26，p = 0.005）。我们的研究结果表明，WM道方向影响温度计算，这表明文物的方向依赖的磁化率可能存在于CST。
The presence of orientation-dependent susceptibility artifacts in magnetic resonance chemical shift thermometry (CST) can confound accurate temperature calculations. Here, we quantify the effect of white matter (WM) tract orientation on CST due to tissue-specific susceptibility. Twenty-nine healthy volunteers (27±4 years old) were scanned on a 3T MR scanner with a 32-channel head coil. Diffusion tensor imaging (DTI), T1-weighted imaging, and single voxel spectroscopy (SVS) for CST were acquired. Participants were then asked to rotate their head ~3 – 5° (yaw or roll) to alter the orientation of WM tracts relative to the external magnetic field. After head rotation, a second SVS scan and T1-weighted imaging were acquired. The WM-fraction-normalized DTI principal eigenvector (V1) images were used to calculate the length of the x-y component of V1, which was used as a surrogate for WM tracts perpendicular to B0. A linear regression model was used to determine the relationship between the perpendicular WM tracts and brain temperature. Significant temperature differences between post- and pre-head rotation scans were observed for brain (−0.72 °C ± 1.36 °C, p = 0.01) but not body (0.012 °C ± 0.07 °C, p = 0.37) temperatures. The difference in brain temperature was positively associated with the corresponding change in perpendicular WM tracts after head rotation (R2 = 0.26, p = 0.005). Our results indicate WM tract orientation affects temperature calculations, suggesting artifacts from orientation-dependent susceptibility may be present in CST.
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DOI：
10.3174/ajnr.a4241
发表时间：
2015-06
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Dehkharghani S;Mao H;Howell L;Zhang X;Pate KS;Magrath PR;Tong F;Wei L;Qiu D;Fleischer C;Oshinski JN
通讯作者：
Oshinski JN
DOI：
10.1073/pnas.0910222107
发表时间：
2010-03-16
影响因子：
11.1
作者：
Lee, Jongho;Shmueli, Karin;Duyn, Jeff H.
通讯作者：
Duyn, Jeff H.
DOI：
10.3174/ajnr.a5059
发表时间：
2017-04
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
Dehkharghani S;Fleischer CC;Qiu D;Yepes M;Tong F
通讯作者：
Tong F
影响因子：
4.2
作者：
Soukup, J;Zauner, A;Bullock, R
通讯作者：
Bullock, R
影响因子：
3.3
作者：
PROVENCHER, SW
通讯作者：
PROVENCHER, SW