TANGOing along the protein secretion pathway.
TANGOing along the protein secretion pathway.
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DOI:
10.1186/gb-2006-7-4-213
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发表时间:
2006
期刊:
影响因子:
12.3
通讯作者:
Kondylis V
中科院分区:
文献类型:
--
作者:
Rabouille C;Kondylis V
An RNAi screen in Drosophila cells has identified about 100 TANGO proteins, which may regulate protein exocytosis or secretion. Although the organization and functions of the constitutive secretory pathway have been intensively studied for decades, a recent genome-wide RNAi screen in Drosophila cells has identified about 100 genes encoding novel so-called TANGO proteins (for transport and Golgi organization) that may be direct regulators of various aspects of protein exocytosis or secretion.
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