Cognitive features 10 or more years after successful breast cancer survival: comparisons across types of cancer interventions.
Cognitive features 10 or more years after successful breast cancer survival: comparisons across types of cancer interventions.
复制标题
成功乳腺癌生存后10年或更长时间的认知特征：对癌症干预类型的比较。
DOI：
10.1002/pon.3086
复制
发表时间：
2013-04
期刊：
影响因子：
3.6
通讯作者：
Schultz, Susan K.
中科院分区：
文献类型：
--
作者：
Nguyen, Christopher M.;Yamada, Torricia H.;Beglinger, Leigh J.;Cavanaugh, Joseph E.;Denburg, Natalie L.;Schultz, Susan K.
本研究调查了65岁及以上乳腺癌幸存者癌症治疗的长期认知影响。将57名女性幸存者与30名健康的老年女性进行比较，年龄和教育程度匹配，没有癌症史。还根据治疗干预对癌症幸存者进行了比较，包括化疗（n = 27）与通过手术和放疗进行的局部治疗（n = 30）。作为一个群体，与正常对照组相比，乳腺癌幸存者在一般认知功能、工作记忆、心理速度和执行功能方面的得分较低。在癌症幸存者中，接受局部治疗的人在语言学习、视觉感知和结构以及视觉注意力和短期保持力方面的得分低于其他幸存者和正常比较。我们的研究结果表明，与匹配的健康受试者相比，老年癌症幸存者的认知结果可能涉及更多与年龄相关的缺陷。
The present study examined the long-term cognitive implications of cancer treatment among breast cancer survivors aged 65 years and older. Fifty-seven women survivors were compared to 30 healthy older female adult comparisons, matched in terms of age and education, with no history of cancer. Cancer survivors were also compared based on treatment intervention, involving chemotherapy (n = 27) versus local therapy through surgery and radiation (n = 30). As a group, the breast cancer survivors scored lower on measures of general cognitive function, working memory, psychomotor speed, and executive function, when compared to the normal comparisons. Among the cancer survivors, those who received local therapy scored lower than the other survivors and normal comparisons on measures of verbal learning, visual perception and construction, as well as visual attention and short-term retention. Our findings suggest that cognitive outcomes may involve more age-related deficits among older cancer survivors compared to matched healthy subjects.
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DOI：
10.1007/s12032-008-9145-0
发表时间：
2009-12
期刊：
Medical oncology (Northwood, London, England)
影响因子：
--
作者：
Raji MA;Tamborello LP;Kuo YF;Ju H;Freeman JL;Zhang DD;Giordano SH;Goodwin JS
通讯作者：
Goodwin JS
影响因子：
8.8
作者：
通讯作者：
--
影响因子：
3.5
作者：
Mehnert, Anja;Scherwath, Angela;Koch, Uwe
通讯作者：
Koch, Uwe
影响因子：
45.3
作者：
Ahles, TA;Saykin, AJ;Silberfarb, PM
通讯作者：
Silberfarb, PM
DOI：
10.1001/archneurpsyc.1945.02300090051008
发表时间：
1945-01-01
影响因子：
--
作者：
BENTON, AL
通讯作者：
BENTON, AL