Cell surface properties of metastatic tumor cells

Cell surface properties of metastatic tumor cells
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转移性肿瘤细胞的细胞表面特性

DOI:
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发表时间:
1982
期刊:
影响因子:
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通讯作者:
G. Nicolson
G. Nicolson
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作者:
G. Nicolson

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由于肿瘤细胞与其环境的相互作用是由细胞表面成分介导的,这种结构被认为在转移中起着最重要的作用。已详细描述了细胞表面性质的修饰,并特别比较了转化细胞与其未转化对应细胞之间的修饰。在这些系统中,细胞表面的修饰通常与肿瘤转化相关(见Hynes[1]、Nicolson[2]和Roblin等人的评论)。[3]);然而,这些变化中很少可能与转移有关[2,4]。使用本卷其他地方描述的动物模型系统(第1章),可以详细检查细胞表面属性及其在转移中的潜在参与。
Since the interaction of tumor cells with their environment is mediated by cell surface constituents, this structure is thought to play one of the most important roles in metastasis. Modifications in cell surface properties have been described in detail and compared in particular, between transformed cells and their untransfor- med counterparts. In these systems modifications at the cell surface have generally correlated with neoplastic transformation (see reviews by Hynes [1], Nicolson [2] and Roblin et al. [3]); however, few of these changes are probably relevant to metastasis [2, 4]. Using the animal model systems described elsewhere in this volume (Chapter 1), it has been possible to examine in detail cell surface properties and their potential involvement in metastasis.
通过在两种聚合物水相中逆流分布对转移性鼠淋巴肉瘤细胞的恶性变体进行细分。
DOI: 10.1021/bi00524a052
发表时间: 1981
期刊: Biochemistry
影响因子: 2.9
作者:
Miner,KM;Walter,H;Nicolson,GL
通讯作者: Nicolson,GL
纤连蛋白在转移性黑色素瘤细胞与内皮细胞及其基底层粘附中的作用。
DOI: 10.1016/0014-4827(81)90191-9
发表时间: 1981
影响因子: 3.7
作者:
Nicolson,GL;Irimura,T;Gonzalez,R;Ruoslahti,E
通讯作者: Ruoslahti,E
纤连蛋白在体外和体内原发和转移部位生长的大鼠乳腺癌克隆细胞系上的分布。
DOI: --
发表时间: 1981
期刊: Cancer research
影响因子: 11.2
作者:
Neri,A;Ruoslahti,E;Nicolson,GL
通讯作者: Nicolson,GL