Vegetable and fruit intake and non-Hodgkin lymphoma survival in Connecticut women.

Vegetable and fruit intake and non-Hodgkin lymphoma survival in Connecticut women.
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DOI:
10.3109/10428191003690364
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发表时间:
2010-06
影响因子:
2.6
通讯作者:
Zhang Y
Zhang Y
中科院分区:
医学4区
文献类型:
--
作者:
Han X;Zheng T;Foss F;Holford TR;Ma S;Zhao P;Dai M;Kim C;Zhang Y;Bai Y;Zhang Y

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我们调查了增加蔬菜和水果的摄入量是否有利于NHL的生存。对1996-2000年在康涅狄格州诊断的568例女性NHL病例进行了中位7.7年的随访。通过考克斯比例风险模型估计校正的风险比(HR)。我们的研究结果表明,诊断前高摄入蔬菜似乎有利于生存超过6个月的NHL患者的总生存率(HR = 0.74,95%CI 0.57-0.98)。特别是,诊断前高摄入绿色叶菜和柑橘类水果分别与死亡风险降低29%(95%CI 0.51-0.98)和27%(95%CI 0.54-0.99)相关。当分别研究不同类型的蔬菜和水果时,发现它们对NHL亚型的影响各不相同。我们的研究表明,增加蔬菜和柑橘类水果的消费可能是一个有用的策略,以提高NHL患者的生存。
We investigated whether an increased intake of vegetables and fruits favors NHL survival. A cohort of 568 female cases of incident NHL diagnosed during 1996–2000 in Connecticut was followed up for a median of 7.7 years. Adjusted hazard ratios (HRs) were estimated by Cox proportional hazard models. Our results show that a pre-diagnostic high intake of vegetables appeared to favor overall survival (HR = 0.74, 95% CI 0.57–0.98) among patients with NHL who survived longer than 6 months. In particular, pre-diagnostic high intakes of green leafy vegetables and citrus fruits were associated with 29% (95% CI 0.51–0.98) and 27% (95% CI 0.54–0.99) reduced risk of death, respectively. When different types of vegetables and fruits were investigated separately, their impacts were found to vary in NHL subtypes. Our study suggests that increasing vegetable and citrus fruit consumption could be a useful strategy to improve survival in NHL patients.
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