New trends in instrumental design for surface plasmon resonance-based biosensors.

New trends in instrumental design for surface plasmon resonance-based biosensors.
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DOI:
10.1016/j.bios.2010.09.030
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发表时间:
2011-01-15
影响因子:
12.6
通讯作者:
Cheng Q
Cheng Q
中科院分区:
工程技术1区
文献类型:
--
作者:
Abbas A;Linman MJ;Cheng Q

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表面等离子体共振(SPR)的生物传感是最先进的无标签,实时检测技术之一。许多具有分歧科学背景的研究小组研究了SPR生物传感器的应用,并研究了导致新的相关仪器的表面等离子体极化子的基本方面。结果,该领域继续处于不断发展的传感技术的最前沿。这篇评论强调了与SPR相关仪器领域的新发展,包括光学平台,芯片设计,纳米级方法和新材料。确定了基于SPR的生物传感的当前趋势,并广泛讨论了SPR生物传感器技术的未来方向。
Surface plasmon resonance (SPR)-based biosensing is one of the most advanced label free, real time detection technologies. Numerous research groups with divergent scientific backgrounds have investigated the application of SPR biosensors and studied the fundamental aspects of surface plasmon polaritons that led to new, related instrumentation. As a result, this field continues to be at the forefront of evolving sensing technology. This review emphasizes the new developments in the field of SPR-related instrumentation including optical platforms, chips design, nanoscale approach and new materials. The current tendencies in SPR-based biosensing are identified and the future direction of SPR biosensor technology is broadly discussed.
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