Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue: The COVID-Rehab Study.
Cardiopulmonary Rehabilitation in Long-COVID-19 Patients with Persistent Breathlessness and Fatigue: The COVID-Rehab Study.
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DOI：
10.3390/ijerph19074133
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发表时间：
2022-03-31
影响因子：
--
通讯作者：
Bherer L
中科院分区：
文献类型：
--
作者：
Besnier F;Bérubé B;Malo J;Gagnon C;Grégoire CA;Juneau M;Simard F;L'Allier P;Nigam A;Iglésies-Grau J;Vincent T;Talamonti D;Dupuy EG;Mohammadi H;Gayda M;Bherer L
(1)背景：COVID-19感染后，心肺和脑功能经常受损。运动康复可能对长期感染COVID-19的患者的康复过程产生重大影响。(2)方法：covid -康复研究将调查8周心肺康复计划对长期covid -19个体心肺健康（O2max）的有效性。次要目标将包括功能能力、生活质量、感知压力、睡眠质量（问卷调查）、呼吸能力（肺活量测定法测试）、凝血、炎症和氧化应激谱（抽血）、认知（神经心理测试）、神经血管耦合和脉搏（fNIRS）。新冠肺炎康复项目是一项随机临床试验，有两个干预组（1:1比例），将进行盲目评估。共招募40人：(1)康复：以中心为基础的运动训练项目（8周，每周3次）；(2)控制：个人将不得不保持他们的日常习惯。(3)结论：目前，对于长期covid -19患者，还没有具体的康复指南，但初步研究结果令人鼓舞。Clinicaltrials.gov (NCT05035628)。
(1) Background: Cardiopulmonary and brain functions are frequently impaired after COVID-19 infection. Exercise rehabilitation could have a major impact on the healing process of patients affected by long COVID-19. (2) Methods: The COVID-Rehab study will investigate the effectiveness of an eight-week cardiopulmonary rehabilitation program on cardiorespiratory fitness (O2max) in long-COVID-19 individuals. Secondary objectives will include functional capacity, quality of life, perceived stress, sleep quality (questionnaires), respiratory capacity (spirometry test), coagulation, inflammatory and oxidative-stress profile (blood draw), cognition (neuropsychological tests), neurovascular coupling and pulsatility (fNIRS). The COVID-Rehab project was a randomised clinical trial with two intervention arms (1:1 ratio) that will be blindly evaluated. It will recruit a total of 40 individuals: (1) rehabilitation: centre-based exercise-training program (eight weeks, three times per week); (2) control: individuals will have to maintain their daily habits. (3) Conclusions: Currently, there are no specific rehabilitation guidelines for long-COVID-19 patients, but preliminary studies show encouraging results. Clinicaltrials.gov (NCT05035628).
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影响因子：
13.8
作者：
Bellan M;Soddu D;Balbo PE;Baricich A;Zeppegno P;Avanzi GC;Baldon G;Bartolomei G;Battaglia M;Battistini S;Binda V;Borg M;Cantaluppi V;Castello LM;Clivati E;Cisari C;Costanzo M;Croce A;Cuneo D;De Benedittis C;De Vecchi S;Feggi A;Gai M;Gambaro E;Gattoni E;Gramaglia C;Grisafi L;Guerriero C;Hayden E;Jona A;Invernizzi M;Lorenzini L;Loreti L;Martelli M;Marzullo P;Matino E;Panero A;Parachini E;Patrucco F;Patti G;Pirovano A;Prosperini P;Quaglino R;Rigamonti C;Sainaghi PP;Vecchi C;Zecca E;Pirisi M
通讯作者：
Pirisi M
DOI：
10.1183/16000617.0101-2018
发表时间：
2019-12-31
期刊：
European respiratory review : an official journal of the European Respiratory Society
影响因子：
--
作者：
Radtke, Thomas;Crook, Sarah;Hebestreit, Helge
通讯作者：
Hebestreit, Helge
影响因子：
3
作者：
Liu, Kai;Zhang, Weitong;Chen, Ying
通讯作者：
Chen, Ying
影响因子：
8.3
作者：
Pendlebury ST;Welch SJ;Cuthbertson FC;Mariz J;Mehta Z;Rothwell PM
通讯作者：
Rothwell PM
DOI：
10.1111/j.1532-5415.2005.53221.x
发表时间：
2005-04-01
影响因子：
6.3
作者：
Nasreddine, ZS;Phillips, NA;Chertkow, H
通讯作者：
Chertkow, H