Whole-genome resource sequences of 57 indigenous Ethiopian goats.

Whole-genome resource sequences of 57 indigenous Ethiopian goats.
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57只埃塞俄比亚山羊的全基因组资源序列。

DOI:
10.1038/s41597-024-02973-2
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发表时间:
2024-01-29
期刊:
影响因子:
9.8
通讯作者:
Mwacharo JM
Mwacharo JM
中科院分区:
综合性期刊2区
文献类型:
--
作者:
Belay S;Belay G;Nigussie H;Jian-Lin H;Tijjani A;Ahbara AM;Tarekegn GM;Woldekiros HS;Mor S;Dobney K;Lebrasseur O;Hanotte O;Mwacharo JM

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家养山羊分布在世界各地,世界上10亿只山羊中约有35%分布在非洲。埃塞俄比亚有5250万只山羊,其中约99.9%被认为是来自游牧民族在遥远的过去引入非洲之角的动物的土著地方品种。整个区域的小农户和半流动牧民继续管理这些农场。我们在这里报告57个山羊基因组从12个埃塞俄比亚山羊种群从不同的农业气候采样。通过在Illumina NovaSeq 6000平台上以9.71x的平均深度和150 bp对端读数对DNA样品进行测序来生成数据。总共生成了约2 TB的原始数据,并且99.8%的干净读段在99.6%的覆盖率下成功映射到山羊参考基因组组装体。大约产生了2476万个SNP。这些SNPs可用于研究山羊在国家、区域和全球层面的种群结构和基因组动态,以揭示该物种的进化轨迹。
Domestic goats are distributed worldwide, with approximately 35% of the one billion world goat population occurring in Africa. Ethiopia has 52.5 million goats, ~99.9% of which are considered indigenous landraces deriving from animals introduced to the Horn of Africa in the distant past by nomadic herders. They have continued to be managed by smallholder farmers and semi-mobile pastoralists throughout the region. We report here 57 goat genomes from 12 Ethiopian goat populations sampled from different agro-climates. The data were generated through sequencing DNA samples on the Illumina NovaSeq 6000 platform at a mean depth of 9.71x and 150 bp pair-end reads. In total, ~2 terabytes of raw data were generated, and 99.8% of the clean reads mapped successfully against the goat reference genome assembly at a coverage of 99.6%. About 24.76 million SNPs were generated. These SNPs can be used to study the population structure and genome dynamics of goats at the country, regional, and global levels to shed light on the species’ evolutionary trajectory.
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期刊: ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
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