Topographical variations in the polarization sensitivity of articular cartilage as determined by polarization-sensitive optical coherence tomography and polarized light microscopy.
Topographical variations in the polarization sensitivity of articular cartilage as determined by polarization-sensitive optical coherence tomography and polarized light microscopy.
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通过偏振敏感光学相干断层扫描和偏振光显微镜测定关节软骨偏振敏感性的地形变化。
DOI:
10.1117/1.2976422
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发表时间:
2008
影响因子:
3.5
通讯作者:
Peavy,GeorgeM
中科院分区:
文献类型:
--
作者:
Xie,Tuqiang;Xia,Yang;Guo,Shuguang;Hoover,Patrick;Chen,Zhongping;Peavy,GeorgeM
To understand the influence of topographical variations in collagen fibril orientation of articular cartilage on optical phase images of polarization-sensitive optical coherence tomography (PS-OCT), we use polarized light microscopy (PLM) to quantify the orientation and phase retardation of the collagen architecture in cartilage at the same locations imaged by PS-OCT. The PS-OCT experiments demonstrate that articular cartilage has normal variations in polarization sensitivity at different locations over an intact bovine tibial plateau. Articular cartilage is not polarization sensitive along the vertical axis on the medial edge and central areas of the joint surface, but becomes polarization sensitive on the lateral edge of the tibia. This difference in optical phase retardation, as demonstrated by PS-OCT, is verified by PLM to be caused by differences in collagen fibril orientation at different locations of the tibial plateau. This study demonstrates that normal topographical variations in the collagen architecture of articular cartilage within a joint have a profound influence on the optical phase retardation detected by PS-OCT imaging, and therefore must be understood and mapped for specific joints before PS-OCT imaging can be used for the evaluation of the health status of individual joint surfaces.
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影响因子:
64.8
作者:
M. W. Sundberg;C. Meares;D. Goodwin;C. Diamanti
通讯作者:
C. Diamanti
DOI:
10.1016/s0047-0740(86)80003-1
发表时间:
1986
期刊:
International journal of nuclear medicine and biology
影响因子:
--
作者:
Y. Arano;A. Yokoyama;Y. Magata;H. Saji;K. Horiuchi;K. Torizuka
通讯作者:
K. Torizuka
影响因子:
9.3
作者:
W. A. Petit;F. Deland;G. Pepper;L. Blanton
通讯作者:
L. Blanton
DOI:
--
发表时间:
1984
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
--
作者:
Kung,HF;Molnar,M;Billings,J;Wicks,R;Blau,M
通讯作者:
Blau,M
DOI:
10.1016/0047-0740(85)90004-x
发表时间:
1985
期刊:
International journal of nuclear medicine and biology
影响因子:
--
作者:
Paik,CH;Phan,LN;Hong,JJ;Sahami,MS;Heald,SC;Reba,RC;Steigman,J;Eckelman,WC
通讯作者:
Eckelman,WC