Golgi-to-plastid trafficking of proteins through secretory pathway: Insights into vesicle-mediated import toward the plastids.

Golgi-to-plastid trafficking of proteins through secretory pathway: Insights into vesicle-mediated import toward the plastids.
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DOI:
10.1080/15592324.2016.1221558
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发表时间:
2016-09
影响因子:
2.9
通讯作者:
Mitsui T
Mitsui T
中科院分区:
生物学4区
文献类型:
--
作者:
Baslam M;Oikawa K;Kitajima-Koga A;Kaneko K;Mitsui T

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质体蛋白质靶向途径的多样性及其对发育和代谢状态的调控是植物细胞功能调控中的一个关键问题。通过调节细胞内生理和代谢变化的反应,将蛋白质靶向进入和穿过质体包膜的基因表达变化的一般输入途径对植物发育至关重要。其中,糖蛋白靶向复杂质体涉及通过分泌途径的路由。然而,对通过这一系统贩运人口的机制仍然知之甚少。本文讨论了我们的研究结果,在特定的N-糖基化的核苷酸焦磷酸酶/磷酸二酯酶(NPPs)糖蛋白和突出的蛋白质传递高尔基体/质体途径通过分泌途径。此外,我们概述的假说,解释机制进口囊泡运输与核编码的蛋白质到质体。
The diversity of protein targeting pathways to plastids and their regulation in response to developmental and metabolic status is a key issue in the regulation of cellular function in plants. The general import pathways that target proteins into and across the plastid envelope with changes in gene expression are critical for plant development by regulating the response to physiological and metabolic changes within the cell. Glycoprotein targeting to complex plastids involves routing through the secretory pathway, among others. However, the mechanisms of trafficking via this system remain poorly understood. The present article discusses our results in site-specific N-glycosylation of nucleotide pyrophosphatase/phosphodiesterases (NPPs) glycoproteins and highlights protein delivery in Golgi/plastid pathway via the secretory pathway. Furthermore, we outline the hypotheses that explain the mechanism for importing vesicles trafficking with nucleus-encoded proteins into plastids.
分类信号,N末端修饰和叶绿体蛋白质组的丰度。
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