Cannabis cue-elicited craving and the reward neurocircuitry.
Cannabis cue-elicited craving and the reward neurocircuitry.
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DOI:
10.1016/j.pnpbp.2011.11.001
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发表时间:
2012-07-02
影响因子:
5.6
通讯作者:
DeWitt, Samuel J.
中科院分区:
文献类型:
--
作者:
Filbey, Francesca M.;DeWitt, Samuel J.
Cue-elicited craving or the intense desire to consume a substance following exposure to a conditioned drug cue is one of the primary behavioral symptoms of substance use disorders (SUDs). While the concept of cue-elicited craving is well characterized in alcohol and other substances of abuse, only recently has it been described in cannabis. A review of the extant literature has established that cue-elicited craving is a powerful reinforcer that contributes to drug-seeking for cannabis. Further, emergent research has begun to identify the neurobiological systems and neural mechanisms associated with this behavior. What research shows is that while theories of THC’s effects on the dopaminergic-reward system remain divergent, cannabis cues elicit neural activation in the brain’s reward network.
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DOI:
10.1038/npp.2009.200
发表时间:
2010-03
期刊:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
影响因子:
--
作者:
通讯作者:
--
影响因子:
1.7
作者:
French, ED;Dillon, K;Wu, XF
通讯作者:
Wu, XF
影响因子:
3.6
作者:
Gardner, EL
通讯作者:
Gardner, EL
影响因子:
17.7
作者:
Kalivas, PW;Volkow, ND
通讯作者:
Volkow, ND
影响因子:
5.5
作者:
JOHNSON, SW;NORTH, RA
通讯作者:
NORTH, RA