A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage.

A prototype device for non-invasive continuous monitoring of intracerebral hemorrhage.
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DOI:
10.1016/j.jneumeth.2012.12.007
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发表时间:
2013-02-15
影响因子:
3
通讯作者:
Shaw, George J.
Shaw, George J.
中科院分区:
医学4区
文献类型:
--
作者:
Korfhagen, Joseph J.;Kandadai, Madhuvanthi A.;Clark, Joseph F.;Adeoye, Opeolu;Shaw, George J.

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开发了一种非侵入性、实时监测设备的原型,用于检测继发于疾病或损伤(如脑出血(ICH))的大脑变化。最终的目标是一种非侵入性的、真实的时间传感器,它可以提醒临床医生昏迷病人的大脑因出血、癫痫发作或中风而发生的变化。在这项工作中,400 MHz的电磁(EM)信号发射的天线(T),入射到一个“脑凝胶”在体外ICH模型,并接收(R)天线。发现接收信号的变化是由血液的存在引起的。发现接收功率(PR)是血液横截面积的线性函数,如垂直于入射波测量的。此外,该传感器能够在1000 mL体外模型中检测到低至1 mL的血液。
A prototype for a non-invasive, real-time, monitoring device was developed to detect changes in the brain secondary to disease or injury such as intracerebral hemorrhage (ICH). The eventual goal is a non-invasive, real time sensor that can alert the clinician to alterations in the comatose patient’s brain resulting from hemorrhage, seizure or stroke. In this work, a 400 MHz electromagnetic (EM) signal was transmitted with an antenna (T), incident on a ‘brain gel’ in vitro ICH model, and received by a receiving (R) antenna. Changes in the received signal were found to be induced by the presence of blood. The received power (PR) was found to be a linear function of the cross sectional area of blood, as measured normal to the incident wave. In addition, the sensor was able to detect as little as 1 mL of blood in this 1000 mL in vitro model.
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