Comparison of electrical conductivities of various brain phantom gels: Developing a 'Brain Gel Model'.
Comparison of electrical conductivities of various brain phantom gels: Developing a 'Brain Gel Model'.
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DOI：
10.1016/j.msec.2012.07.024
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发表时间：
2012-12-01
影响因子：
7.9
通讯作者：
Shaw, George J.
中科院分区：
文献类型：
--
作者：
Kandadai, Madhuvanthi A.;Raymond, Jason L.;Shaw, George J.
使用导电凝胶来模拟大脑和其他组织在新医疗设备的开发中越来越受到关注。目前，很少有这样的模型可以在生理温度下使用。在这项工作中，琼脂、琼脂糖和明胶凝胶的电导率通过在 0–1 mg/ml 范围内改变 NaCl 浓度来控制。交流电导率是在室温和生理温度 (37°C) 下、100–500 Hz 频率范围内测量的。电导率 (σ) 几乎与频率无关，但随 NaCl 浓度线性增加，并且在这些凝胶的生理温度下更高。为每种凝胶类型导出了预测电导率与 NaCl 浓度函数关系的公式。总体目标是开发“脑凝胶模型”，用于研究生理温度下大脑和其他组织的低频电特性。
The use of conducting gels to mimic brain and other tissues is of increasing interest in the development of new medical devices. Currently, there are few such models that can be utilized at physiologic temperatures. In this work, the conductivities of agar, agarose and gelatin gels were manipulated by varying NaCl concentration from 0–1 mg/ml. The AC conductivity was measured at room and physiological temperatures (37°C) in the 100–500 Hz frequency range. Conductivity (σ) was nearly independent of frequency but increased linearly with NaCl concentration and was higher at physiological temperatures in these gels. A formula for predicting conductivity as a function of NaCl concentration was derived for each gel type. The overall goal is to develop a ‘brain gel model’, for studying low frequency electrical properties of the brain and other tissues at physiological temperatures.
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影响因子：
19.7
作者：
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通讯作者：
Goldberg, SN
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作者：
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作者：
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通讯作者：
Peters, TM