Stem Cells for Aging-Related Disorders.
Stem Cells for Aging-Related Disorders.
复制标题
DOI:
10.1007/s12015-021-10222-x
复制
发表时间:
2021-12
影响因子:
4.8
通讯作者:
Steinberg GK
中科院分区:
文献类型:
--
作者:
Borlongan MC;Farooq J;Sadanandan N;Wang ZJ;Cozene B;Lee JY;Steinberg GK
This review captures recent advances in biological and translational research on stem cells. In particular, we discuss new discoveries and concepts regarding stem cell treatment of aging-related disorders. A myriad of stem cell sources exists, from hematopoietic to mesenchymal and neural cell lineages. We examine current applications of exogenous adult bone marrow-derived stem cells as an effective and safe transplantable cell source, as well as the use of electrical stimulation to promote endogenous neurogenesis for Parkinson’s disease. We also explore the potential of transplanting exogenous umbilical cord blood cells and mobilizing host resident stem cells in vascular dementia and aging. In addition, we assess the ability of small molecules to recruit resident stem cells in Alzheimer’s disease. Finally, we evaluate mechanisms of action recently implicated in stem cell therapy, such as the role of long non-coding RNAs, G-protein coupled receptor 5, and NeuroD1. Our goal is to provide a synopsis of recent milestones regarding the application of stem cells in aging.
登录
查看更多内容
影响因子:
9
作者:
Rosati J;Ferrari D;Altieri F;Tardivo S;Ricciolini C;Fusilli C;Zalfa C;Profico DC;Pinos F;Bernardini L;Torres B;Manni I;Piaggio G;Binda E;Copetti M;Lamorte G;Mazza T;Carella M;Gelati M;Valente EM;Simeone A;Vescovi AL
通讯作者:
Vescovi AL
影响因子:
11
作者:
Jankovic, Joseph;Tan, Eng King
通讯作者:
Tan, Eng King
影响因子:
4.8
作者:
Lee, Jea-Young;Tuazon, Julian P.;Borlongan, Cesario V.
通讯作者:
Borlongan, Cesario V.
DOI:
10.1002/mds.115
发表时间:
2018-12
期刊:
Movement disorders : official journal of the Movement Disorder Society
影响因子:
--
作者:
Habets JGV;Heijmans M;Kuijf ML;Janssen MLF;Temel Y;Kubben PL
通讯作者:
Kubben PL
影响因子:
4.8
作者:
Jiang MQ;Yu SP;Wei ZZ;Zhong W;Cao W;Gu X;Wu A;McCrary MR;Berglund K;Wei L
通讯作者:
Wei L