Change in the capability of reactive oxygen species production by neutrophils following weight reduction in female judoists
Change in the capability of reactive oxygen species production by neutrophils following weight reduction in female judoists
复制标题
女性柔道运动员体重减轻后中性粒细胞产生活性氧能力的变化
DOI：
10.1136/bjsm.2006.032029
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发表时间：
2007
影响因子：
18.4
通讯作者：
S. Nakaji
中科院分区：
文献类型：
--
作者：
Makoto Yaegaki;T. Umeda;I. Takahashi;M. Matsuzaka;Norio Sugawara;S. Shimaya;M. Tanabe;A. Kojima;N. Mochida;Yousuke Yamamoto;S. Nakaji
目的：运动员减肥被认为是更容易感染。关于运动员体重减轻介导的中性粒细胞功能和相关活性（如活性氧（ROS）产生能力、吞噬活性（PA）和血清调理活性（SOA））的变化的研究很少。研究方法：对16名日本女大学柔道运动员进行了为期20天的赛前训练，在训练的第一天（赛前值）和最后一天（赛后值）的清晨进行了检查。16例受试者中，8例需要减肥（WR组），另8例不需要减肥（对照组）。评估的参数是中性粒细胞计数、血清免疫球蛋白和补体、生肌酶、ROS产生能力、PA和SOA。结果：与治疗前相比，治疗后两组的ROS产生均显著增加（P<0.01）。PA在WR组显著降低（p<0.05），对照组也降低，但降低不显著。对照组的SOA显著增加（p<0.05），而WR组无显著变化。结论：WR组的变化可能是减肥方案与运动方案相结合的直接结果，表明中性粒细胞参数（ROS产生，PA和SOA）往往偏离其典型的代偿性变化，以维持免疫系统稳态。
Objective: Athletes undergoing weight reduction are recognised as being more prone to infection. Few studies exist for athletes on the weight reduction-mediated changes in neutrophil function and related activities such as reactive oxygen species (ROS) production capability, phagocytic activity (PA) and serum opsonic activity (SOA). Methods: 16 Japanese female university judoists were examined in the early morning of the first day (pre-values) and the last day (post-values) of a 20-day pre-competition training period. Of the 16 subjects, 8 needed to reduce weight (WR group) and the other 8 did not (control group). The parameters assessed were the neutrophil count, serum immunoglobulins and complements, myogenic enzymes, ROS production capability, PA and SOA. Results: Comparing the post-values with the pre-values, ROS production significantly increased in both groups (p<0.01 for both). PA significantly decreased in the WR group (p<0.05); it also decreased in the control group but the decrease was not significant. SOA significantly increased in the control group (p<0.05), but showed no significant change in the WR group. Conclusions: The changes in the WR group were probably a direct consequence of the weight-reduction regimen coupled with the exercise regimen, suggesting that neutrophil parameters (ROS production, PA and SOA) had tended to deviate from their typical compensatory changes to maintain immune system homoeostasis.
DOI：
10.1093/clinids/11.supplement_7.s1532
发表时间：
1989-11
期刊：
Reviews of infectious diseases
影响因子：
--
作者：
Daniel W. Sawyer;G. Donowitz;G. L. Mandell
通讯作者：
Daniel W. Sawyer;G. Donowitz;G. L. Mandell
Fc 和补体受体的结构和调节。
DOI：
10.1007/978-1-4757-4862-8_6
发表时间：
1984
期刊：
Contemporary topics in immunobiology
影响因子：
--
作者：
Unkeless,JC;Wright,SD
通讯作者：
Wright,SD