Brain mechanisms underlying the impact of attachment-related stress on social cognition.
Brain mechanisms underlying the impact of attachment-related stress on social cognition.
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DOI：
10.3389/fnhum.2013.00816
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发表时间：
2013
影响因子：
2.9
通讯作者：
Pelphrey KA
中科院分区：
文献类型：
--
作者：
Nolte T;Bolling DZ;Hudac CM;Fonagy P;Mayes L;Pelphrey KA
心理化，特别是成功地将复杂的心理状态归因于他人，对于导航社交互动至关重要。这种能力受到日常生活中外部因素的高度影响，例如压力。我们调查了压力对成年人心智化大脑基础的影响。使用一种新的修改阅读心灵的眼睛测试（RMET-R），我们比较了两个个性化的压力诱导程序的差异影响：一般的压力诱导（GSI）和依恋相关的压力诱导（ASI）。参与者在基线和两次诱导后进行RMET-R。基线结果复制和扩展了先前关于RMET-R神经相关性的发现。此外，我们确定了与从相同刺激做出复杂年龄判断相关的大脑区域。应激暴露后的结果显示，ASI条件导致左侧后上级颞沟（STS），左侧额下回和左侧颞顶交界处（TPJ）的心理化相关激活减少。此外，左额中回和左前额叶与左后STS的功能连接在ASI后增强。我们的研究结果表明，依恋相关的压力有一个独特的影响心理化的神经相关。
Mentalizing, in particular the successful attribution of complex mental states to others, is crucial for navigating social interactions. This ability is highly influenced by external factors within one's daily life, such as stress. We investigated the impact of stress on the brain basis of mentalization in adults. Using a novel modification of the Reading the Mind in the Eyes Test (RMET-R) we compared the differential effects of two personalized stress induction procedures: a general stress induction (GSI) and an attachment-related stress induction (ASI). Participants performed the RMET-R at baseline and after each of the two inductions. Baseline results replicated and extended previous findings regarding the neural correlates of the RMET-R. Additionally, we identified brain regions associated with making complex age judgments from the same stimuli. Results after stress exposure showed that the ASI condition resulted in reduced mentalization-related activation in the left posterior superior temporal sulcus (STS), left inferior frontal gyrus and left temporoparietal junction (TPJ). Moreover, the left middle frontal gyrus and left anterior insula showed greater functional connectivity to the left posterior STS after the ASI. Our findings indicate that attachment-related stress has a unique effect on the neural correlates of mentalization.
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DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
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