Randomized web-based physical activity intervention in adolescent survivors of childhood cancer.
Randomized web-based physical activity intervention in adolescent survivors of childhood cancer.
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DOI:
10.1002/pbc.27216
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发表时间:
2018-08
影响因子:
3.2
通讯作者:
Ness KK
中科院分区:
文献类型:
--
作者:
Howell CR;Krull KR;Partin RE;Kadan-Lottick NS;Robison LL;Hudson MM;Ness KK
Healthy lifestyle choices including participation in regular physical activity may improve health outcomes in survivors of childhood cancer. We aimed to evaluate the efficacy of a web-delivered, physical activity intervention among adolescent survivors to increase moderate-to-vigorous physical activity (MVPA) and improve fitness, neurocognitive and health-related quality of life (HRQoL) over 24-weeks. This randomized controlled trial was conducted among survivors (aged ≥ 11 to < 15 years) treated at a single institution. Participants were randomized to either a physical activity intervention delivered over the internet or a control group. The intervention group received educational materials, an activity monitor and access to an interactive website designed to motivate increased physical activity via rewards; the control group received an activity monitor and educational materials. Physical activity, fitness, neurocognitive and HRQoL outcomes were assessed at baseline and 24-weeks. Mean changes were compared between groups using paired t-tests. Of 97 survivors enrolled, 78 completed the study, mean age was 12.7 (SD 1.1), 80% were white, and 55.1% were female. Fifty-three survivors were assigned to the intervention and 25 to the control group. While survivors in the intervention group increased, and those in the control group decreased (4.7±119.9 vs. −24.3±89.7 minutes) weekly MVPA, this difference was not significant (p=0.30). However, hand grip strength, number of sit-ups and pushups, neurocognitive function, and HRQoL outcomes improved in the intervention, but not in the control group. An interactive, rewards based intervention designed to increase MVPA is feasible in adolescent survivors of childhood cancer.
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