A 5-year-old girl with a congenital ganglioneuroma diagnosed by fine needle aspiration biopsy: a case report.

A 5-year-old girl with a congenital ganglioneuroma diagnosed by fine needle aspiration biopsy: a case report.
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DOI:
10.1186/1742-6413-5-5
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发表时间:
2008-03-30
期刊:
影响因子:
1.9
通讯作者:
Barboza-Quintana O
Barboza-Quintana O
中科院分区:
医学4区
文献类型:
--
作者:
Ponce-Camacho MA;Diaz de Leon-Medina R;Miranda-Maldonado I;Garza-Guajardo R;Hernandez-Salazar J;Barboza-Quintana O

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神经节细胞瘤是一种罕见的良性神经母细胞瘤,主要发生于中枢或周围自主神经系统,尤其是交感神经系统。最易受影响的解剖部位是后纵隔、腹膜后、肾上腺和头颈部软组织。在目前的文献中,神经节细胞瘤的细针穿刺诊断和细胞学表现的报告很少。一个5岁的女孩提出了一个肿块在颈部区域自出生。实验室常规检查在正常范围内,超声检查显示颈部软组织中存在一个实体且边界清楚的病变。进行细针穿刺活检,获得的涂片显示成熟神经节细胞和梭形细胞群的混合物,提示雪旺细胞来源。建议诊断为节细胞神经瘤。穿刺活检和手术切除证实了这一诊断。摘要颈部先天性节细胞神经瘤是一种罕见的神经母细胞来源的软组织良性肿瘤,在小儿头颈部软组织肿瘤的鉴别诊断中应加以考虑。细针穿刺活检技术是一种可靠的方法,可以使用与儿童软组织肿瘤处理的信心。
Ganglioneuroma is a rare, benign, neuroblastic tumor arising mainly from the central or peripheral autonomic nervous system, especially the sympathetic system. The most affected anatomical sites are the posterior mediastinum, retroperitoneum, adrenal gland and head and neck soft tissue. In the current literature, reports of ganglioneuroma diagnosed by fine-needle aspiration and its cytological appearance are scarce. A 5-year-old girl presented with a mass in the cervical region since birth. Laboratory routine tests were within normal limits, ultrasonography demonstrated a solid and well-circumscribed lesion in the soft tissues of the cervical region. Fine needle aspiration biopsy was carried out, and the obtained smears showed a mixture of mature ganglion cells and groups of spindle cells suggestive of schwann cell origin. A diagnosis of ganglioneuroma was suggested. Core biopsy and surgical resection confirmed this diagnosis. Congenital ganglioneuroma of the cervical region is an uncommon soft tissue benign neoplasm of neuroblastic origin, and it should be considered in the differential diagnosis of head and neck pediatric soft tissue tumors. Fine needle aspiration biopsy technique is a reliable method that can be used with confidence when dealing with pediatric soft tissue tumors.
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