Oral squamous cell carcinoma: etiology, pathogenesis and prognostic value of genomic alterations.

Oral squamous cell carcinoma: etiology, pathogenesis and prognostic value of genomic alterations.
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口腔鳞状细胞癌:基因组改变的病因、发病机制和预后价值。

DOI:
--
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发表时间:
2006
影响因子:
1
通讯作者:
Sunita Yadav
Sunita Yadav
中科院分区:
医学4区
文献类型:
--
作者:
R. Mehrotra;Sunita Yadav

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被引文献

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头颈部肿瘤是一组重要的肿瘤,其发病率在世界许多地区正在增加。尽管现代医学取得了巨大进步,但这一增幅仍然很高。这种恶性肿瘤在发展中国家更为普遍,但不幸的是,它并没有像发达国家更普遍的癌症(如肺癌、乳腺癌或结肠癌)那样受到足够的关注。这些病变的诊断和治疗技术的最新进展产生了新的分子靶标,揭示了信号通路的优势和先进的早期癌症检测。这篇综述涵盖了我们对病因学、分子变化以及基因组和蛋白质组学研究在诊断和有效治疗这一现代祸害中可能发挥的作用的理解的最新进展。
Tumours of the head and neck comprise an important group of neoplasia, the incidence of which is increasing in many parts of the world. This increase remains high, despite all the advances in modern medicine. This malignancy is more prevalent in the developing world and unfortunately, has not received satisfactory attention as the more prevalent cancers of the developed world, like lung, breast, or colon cancer. Recent advances in diagnosis and therapeutic techniques of these lesions have yielded novel molecular targets, uncovered signal pathway dominance and advanced early cancer detection. This review covers recent advances in our understanding of the etiology, molecular changes and the possible role that genomic and proteomic research might play in the diagnosis and effective cure of this modern-day scourge.
酒精与癌症。
DOI: 10.1007/978-1-4613-1835-4_34
发表时间: 1986
影响因子: --
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通讯作者: Conner,MW
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