Risk and protective factors for self-harm and suicide in children and adolescents: a systematic review and meta-analysis protocol.

Risk and protective factors for self-harm and suicide in children and adolescents: a systematic review and meta-analysis protocol.
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DOI:
10.1136/bmjopen-2021-058297
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发表时间:
2022-11-25
期刊:
影响因子:
2.9
通讯作者:
Ougrin, Dennis
Ougrin, Dennis
中科院分区:
医学3区
文献类型:
--
作者:
Farbstein, Dan;Lukito, Steve;Yorke, Isabel;Wilson, Emma;Crudgington, Holly;El-Aalem, Omar;Cliffe, Charlotte;Bergou, Nicol;Itani, Lynn;Owusu, Andy;Sedgwick, Rosemary;Singh, Nidhita;Tarasenko, Anna;Tucker, Gavin;Woodhouse, Emma;Suzuki, Mimi;Myerscough, Anna Louise;Lopez Chemas, Natalia;Abdel-Halim, Nadia;Del Giovane, Cinzia;Epstein, Sophie;Ougrin, Dennis

文献摘要

参考文献

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自残和自杀是儿童和青少年的主要公共卫生问题。许多自杀和自残的风险和保护因素已经在文献中被确定和报道。然而,这些已确定的风险和保护因素的指导评估和管理的能力由于数量众多而有限。本协议描述了一项正在进行的系统审查和荟萃分析,旨在检查儿童和青少年自残和自杀风险因素的纵向研究,对各种自残和自杀风险因素的关联强度进行比较,并阐明那些需要进一步调查的因素。我们使用EMBASE、PsycINFO、Medline、CINAHL和HMIC数据库对从开始到2020年10月28日的文献进行系统检索,检索将在系统综述发表前更新。此外,我们将联系该领域的专家,包括其同行评议出版物被纳入我们系统综述的主要研究人员,以及我们广泛的研究网络中的研究人员,我们将搜索相关综述的参考文献列表,以检索我们搜索中未确定的任何文章。我们将提取相关数据,并提出一种叙事综合,并在有足够数据的meta分析中结合结果。我们将使用纽卡斯尔-渥太华量表评估每项研究的偏倚风险,并对每项风险或保护因素的证据的数量和质量进行总结。由于这是对文献的系统回顾,因此不会寻求伦理批准。研究结果将发表在心理健康期刊上,并在以自杀预防为重点的会议上发表。CRD42021228212。
Self-harm and suicide are major public health concerns among children and adolescents. Many risk and protective factors for suicide and self-harm have been identified and reported in the literature. However, the capacity of these identified risk and protective factors to guide assessment and management is limited due to their great number. This protocol describes an ongoing systematic review and meta-analysis which aims to examine longitudinal studies of risk factors for self-harm and suicide in children and adolescents, to provide a comparison of the strengths of association of the various risk factors for self-harm and suicide and to shed light on those that require further investigation. We perform a systematic search of the literature using the databases EMBASE, PsycINFO, Medline, CINAHL and HMIC from inception up to 28 October 2020, and the search will be updated before the systematic review publication. Additionally, we will contact experts in the field, including principal investigators whose peer-reviewed publications are included in our systematic review as well as investigators from our extensive research network, and we will search the reference lists of relevant reviews to retrieve any articles that were not identified in our search. We will extract relevant data and present a narrative synthesis and combine the results in meta-analyses where there are sufficient data. We will assess the risk of bias for each study using the Newcastle–Ottawa Scale and present a summary of the quantity and the quality of the evidence for each risk or protective factor. Ethical approval will not be sought as this is a systematic review of the literature. Results will be published in mental health journals and presented at conferences focused on suicide prevention. CRD42021228212.
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