Genomic signatures associated with maintenance of genome stability and venom turnover in two parasitoid wasps.
Genomic signatures associated with maintenance of genome stability and venom turnover in two parasitoid wasps.
复制标题
DOI：
10.1038/s41467-022-34202-y
复制
发表时间：
2022-10-27
影响因子：
16.6
通讯作者：
中科院分区：
文献类型：
--
作者：
寄生蜂正迅速发展成为进化生物学的模型。在这里，我们提出了两个平腹蜂，A。和A. fulloi，并利用这些基因组研究两个基本问题-基因组大小进化和毒液进化。平腹蜂的基因组比其他黄蜂已知的要大得多，并且最近出人意料地爆发了LTR逆转录转座子。重要的是，一些基因组创新，包括Piwi基因家族扩增，无处不在的Piwi表达谱，以及转座因子-piRNA协同进化，可能已经出现转座因子沉默，以维持基因组稳定性。此外，我们表明，共同选择进化所产生的表达变化在毒液腺中起着主导作用的毒液营业额。我们还强调了在毒液进化过程中与毒液基因共表达的非毒液基因的潜在重要性。我们的研究结果极大地推进了目前对基因组大小进化和毒液进化的理解，这些基因组资源将有助于未来昆虫的比较基因组学研究。寄生蜂正迅速发展成为进化生物学的模型。在这里，作者分析了两种平腹蜂的基因组，揭示了与维持基因组稳定性和毒液基因快速周转有关的基因组创新。
Parasitoid wasps are rapidly developing as a model for evolutionary biology. Here we present chromosomal genomes of two Anastatus wasps, A. japonicus and A. fulloi, and leverage these genomes to study two fundamental questions—genome size evolution and venom evolution. Anastatus shows a much larger genome than is known among other wasps, with unexpectedly recent bursts of LTR retrotransposons. Importantly, several genomic innovations, including Piwi gene family expansion, ubiquitous Piwi expression profiles, as well as transposable element-piRNA coevolution, have likely emerged for transposable element silencing to maintain genomic stability. Additionally, we show that the co-option evolution arose by expression shifts in the venom gland plays a dominant role in venom turnover. We also highlight the potential importance of non-venom genes that are coexpressed with venom genes during venom evolution. Our findings greatly advance the current understanding of genome size evolution and venom evolution, and these genomic resources will facilitate comparative genomics studies of insects in the future. Parasitoid wasps are rapidly developing as a model for evolutionary biology. Here, the authors analyze the genomes of two Anastatus wasps, revealing genomic innovations related to maintenance of genomic stability, and rapid turnover of venom genes.
登录
查看更多内容
影响因子：
5.8
作者：
Cong, Yuyang;Ye, Xinhai;Mei, Yang;He, Kang;Li, Fei
通讯作者：
Li, Fei
影响因子：
4.9
作者：
Bao W;Kojima KK;Kohany O
通讯作者：
Kohany O
影响因子：
48
作者：
Cheng H;Concepcion GT;Feng X;Zhang H;Li H
通讯作者：
Li H
影响因子：
5.3
作者：
Branstetter MG;Childers AK;Cox-Foster D;Hopper KR;Kapheim KM;Toth AL;Worley KC
通讯作者：
Worley KC
影响因子：
3.7
作者：
Allen JD;Xie Y;Chen M;Girard L;Xiao G
通讯作者：
Xiao G