Fabrication of magneto-controlled moveable architecture to develop reusable electrochemical biosensors.
Fabrication of magneto-controlled moveable architecture to develop reusable electrochemical biosensors.
复制标题
制造磁控可移动结构以开发可重复使用的电化学生物传感器
DOI:
10.1038/srep04169
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发表时间:
2014-02-25
影响因子:
4.6
通讯作者:
Li G
中科院分区:
文献类型:
--
作者:
Zhu X;Feng C;Ye Z;Chen Y;Li G
Electrochemical biosensors have been studied intensively for several decades. Numerous sensing concepts and related interface architectures have been developed. However, all such architectures suffer a trade-off: simple architectures favour usability, whereas complex architectures favour better performance. To overcome this problem, we propose a novel concept by introducing a magneto-controlled moveable architecture (MCMA) instead of the conventional surface-fixed architecture. As a model, human breast cancer cells were used in this study. The results showed that a detection range from 100 to 1 × 106cells could be achieved. Moreover, the whole detection cycle, including the measurement and the regeneration, could be completed in only 2 min. Thus, usability and excellent performance can be achieved in a single biosensor.
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影响因子:
17.1
作者:
Mani, Vigneshwaran;Chikkaveeraiah, Bhaskara V.;Patel, Vyomesh;Gutkind, J. Silvio;Rusling, James F.
通讯作者:
Rusling, James F.
影响因子:
16.6
作者:
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通讯作者:
Jiang, Qing
DOI:
10.1073/pnas.1201547109
发表时间:
2012-07-17
影响因子:
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作者:
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通讯作者:
Wightman, R. Mark
影响因子:
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作者:
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通讯作者:
Jelen, Frantisek
影响因子:
5.4
作者:
Luo, Xiaoteng;Xu, Jingjing;Hsing, I-Ming
通讯作者:
Hsing, I-Ming