The Texas Children's Medication Algorithm Project: report of the Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder.
The Texas Children's Medication Algorithm Project: report of the Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder.
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德克萨斯州儿童药物算法项目：德克萨斯州共识会议小组关于儿童重度抑郁症药物治疗的报告。
DOI：
10.1097/00004583-199911000-00020
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
Rush,AJ
中科院分区：
文献类型：
--
作者：
Hughes,CW;Emslie,GJ;Crismon,ML;Wagner,KD;Birmaher,B;Geller,B;Pliszka,SR;Ryan,ND;Strober,M;Trivedi,MH;Toprac,MG;Sedillo,A;Llana,ME;Lopez,M;Rush,AJ
在缺乏科学依据和临床意见的情况下，根据科学证据和临床意见制定儿童重性抑郁症（MDD）药物治疗算法的共识指南。这种方法的最终目标是综合研究和临床经验的从业者，并增加儿童MDD首选治疗的统一性。最终的目标是开发一种方法，可以测试它是否可以改善MDD儿童和青少年的临床结局。参与者包括学术临床医生和研究人员，执业临床医生，管理人员，消费者和家庭。重点是审查和使用临床证据来推荐治疗儿童和青少年抑郁症的具体药理方法。在一系列当前研究证据的陈述和小组讨论之后，共识小组开会，同意假设，并起草算法。这个过程最初提出了治疗策略，然后提出了实施这些策略的策略，并开发了针对严重抑郁症（伴或不伴精神病）和共病注意力缺陷障碍的算法。治疗策略强调使用选择性阿曲库溴铵再摄取抑制剂。该算法包括治疗干预的系统策略和实施策略的推荐策略，包括药物强化和药物组合。与会者建议前瞻性评估的算法在各种公共部门的设置，和许多志愿者作为网站这样的evaluation.CONCLUSIONSSUsing科学和临床经验，共识派生的算法与MDD的儿童和青少年可以开发。
OBJECTIVESTo develop consensus guidelines for medication treatment algorithms for childhood major depressive disorder (MDD) based on scientific evidence and clinical opinion when science is lacking. The ultimate goal of this approach is to synthesize research and clinical experience for the practitioner and to increase the uniformity of preferred treatment for childhood MDD. A final goal is to develop an approach that can be tested as to whether it improves clinical outcomes for children and adolescents with MDD.METHODA consensus conference was held. Participants included academic clinicians and researchers, practicing clinicians, administrators, consumers, and families. The focus was to review and use clinical evidence to recommend specific pharmacological approaches for treatment of MDD in children and adolescents. After a series of presentations of current research evidence and panel discussion, the consensus panel met, agreed on assumptions, and drafted the algorithms. The process initially addressed strategies of treatment and then tactics to implement the strategies.RESULTSConsensually agreed-upon algorithms for major depressions (with and without psychosis) and comorbid attention deficit disorders were developed. Treatment strategies emphasized the use of selective serotonir reuptake inhibitors. The algorithm consists of systematic strategies for treatment interventions and recommended tactics for implementation of the strategies, including medication augmentation and medication combinations. Participants recommended prospective evaluation of the algorithms in various public sector settings, and many volunteered as sites for such an evaluation.CONCLUSIONSUsing scientific and clinical experience, consensus-derived algorithms for children and adolescents with MDD can be developed.
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青少年重度抑郁症中的 MAOIs 对三环类抗抑郁药无反应。
影响因子：
13.3
作者：
N. Ryan;J. Puig;H. Rabinovich;J. Fried;P. Ambrosini;V. Meyer;D. Torres;S. Dachille;D. Mazzie
通讯作者：
D. Mazzie
青春期前妄想性抑郁症与三环类抗抑郁药治疗相关的混合躁狂：三例。
影响因子：
1.9
作者：
M. Strober
通讯作者：
M. Strober
DOI：
--
发表时间：
1995
期刊：
Nature Network Boston
影响因子：
--
作者：
G. Gabbard
通讯作者：
G. Gabbard
焦虑症心理社会治疗的进展。
影响因子：
--
作者：
David H. Barlow;Cassandra L. Lehman
通讯作者：
Cassandra L. Lehman
DOI：
--
发表时间：
1998
期刊：
The Journal of clinical psychiatry.
影响因子：
--
作者：
Rush,AJ;Crismon,ML;Toprac,MG;Trivedi,MH;Rago,WV;Shon,S;Altshuler,KZ
通讯作者：
Altshuler,KZ