Hand gesture performance is impaired in major depressive disorder: A matter of working memory performance?
Hand gesture performance is impaired in major depressive disorder: A matter of working memory performance?
复制标题
重度抑郁症患者的手势表现受损：工作记忆表现的问题？
DOI：
10.1016/j.jad.2021.05.055
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发表时间：
2021-09-01
影响因子：
6.6
通讯作者：
Walther S
中科院分区：
文献类型：
--
作者：
Pavlidou A;Viher PV;Bachofner H;Weiss F;Stegmayer K;Shankman SA;Mittal VA;Walther S
目的患有抑郁症的人表现出许多人际交往缺陷。由于有效使用手势对于社交沟通至关重要，因此抑郁症患者的人际交往缺陷可能是由于手势表现缺陷造成的。因此，本研究比较了抑郁症患者和对照者的手势表现，并检查这些缺陷是否与认知功能障碍和其他领域的功能障碍有关。方法使用上肢失用测试（TULIA）对 30 名抑郁症患者和 30 名对照者的手势表现进行了评估。通过评估临床评定量表来确定手势缺陷是否与运动、认知或功能结果相关。结果与对照组相比，抑郁症患者表现出手势表现受损，其中 2/3 的患者表现出手势缺陷。在抑郁症患者中，手势表现与工作记忆能力高度相关。相比之下，在患者中没有观察到手势表现与手势知识、精神运动迟缓、抑郁严重程度或额叶功能障碍之间的关联。 局限性这是一项横断面研究，较大的研究规模可以自信地检测到更微妙但潜在相关的影响。结论抑郁症患者的手势表现受损，并且似乎与工作记忆能力差有关，这表明手势线索的检索受到干扰，而手势线索表明可能与社会功能相关的独特临床现象。
ObjectiveIndividuals with depression exhibit numerous interpersonal deficits. As effective use of gestures is critical for social communication, it is possible that depressed individuals’ interpersonal deficits may be due to deficits in gesture performance. The present study thus compared gesture performance of depressed patients and controls and examined whether these deficits relate to cognitive and other domains of dysfunction.MethodsGesture performance was evaluated in 30 depressed patients and 30 controls using the Test of Upper Limb Apraxia (TULIA). Clinical rating scales were assessed to determine if gesture deficits were associated with motor, cognitive or functional outcomes.ResultsCompared to controls, depressed patients exhibited impaired gesture performance with 2/3 of the patients demonstrating gesture deficits. Within depressed patients, gesture performance was highly correlated with working memory abilities. In contrast, no association between gesture performance and gestural knowledge, psychomotor retardation, depression severity, or frontal dysfunction was observed in patients.LimitationsThis is a cross-sectional study and a larger size would have allowed for confident detection of more subtle, but potentially relevant effects.ConclusionGesture performance is impaired in depressed patients, and appears to be related to poor working memory abilities, suggesting a disruption in the retrieval of gestural cues indicative of a distinct clinical phenomenon that might be related to social functioning.
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影响因子：
4.6
作者：
Douglas, Katie M.;Porter, Richard J.;Alsop, Brent
通讯作者：
Alsop, Brent
DOI：
10.1037/emo0000436
发表时间：
2019-04
期刊：
Emotion (Washington, D.C.)
影响因子：
--
作者：
Gorlin EI;Werntz AJ;Fua KC;Lambert AE;Namaky N;Teachman BA
通讯作者：
Teachman BA
影响因子：
8.2
作者：
Kelly, Spencer D.;Ozyurek, Asli;Maris, Eric
通讯作者：
Maris, Eric
影响因子：
3.4
作者：
Cook, Susan Wagner;Mitchell, Zachary;Goldin-Meadow, Susan
通讯作者：
Goldin-Meadow, Susan
影响因子：
5.7
作者：
Fridman, EA;Immisch, I;Hallett, M
通讯作者：
Hallett, M