Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions.
Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions.
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DOI：
10.3390/nu15040827
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发表时间：
2023-02-06
期刊：
影响因子：
5.9
通讯作者：
Potenza MN
中科院分区：
文献类型：
--
作者：
Mestre-Bach G;Potenza MN
奖励系统与行为成瘾高度相关，例如赌博障碍（GD）、网络游戏障碍（IGD）以及食物成瘾/暴食症（FA/BED）。在其他大脑区域中，腹侧纹状体（VS）与奖励处理有关。本前沿综述的主要目的是深入探究腹侧纹状体在赌博障碍、网络游戏障碍以及食物成瘾/暴食症中的具体作用，并将其理解为这些病症的一种可能的生物标志物。本文讨论了分析针对这些病症进行干预后大脑变化的研究，尤其是那些探索了腹侧纹状体可能出现的与治疗相关变化的研究。关于行为成瘾的现有治疗方法（包括药物治疗和心理行为治疗）如何影响腹侧纹状体及相关回路的激活，还需要更多的证据。
The reward system is highly relevant to behavioral addictions such as gambling disorder (GD), internet gaming disorder (IGD), and food addiction/binge eating disorder (FA/BED). Among other brain regions, the ventral striatum (VS) has been implicated in reward processing. The main objective of the present state-of-the-art review was to explore in depth the specific role of the VS in GD, IGD and FA/BED, understanding it as a possible biomarker of these conditions. Studies analyzing brain changes following interventions for these disorders, and especially those that had explored possible treatment-related changes in VS, are discussed. More evidence is needed on how existing treatments (both pharmacological and psychobehavioral) for behavioral addictions affect the activation of the VS and related circuitry.
影响因子：
4.7
作者：
Kim J;Kim H;Kang E
通讯作者：
Kang E
影响因子：
7.8
作者：
Kor, Ariel;Djalovski, Amir;Potenza, Marc N.;Zagoory-Sharon, Orna;Feldman, Ruth
通讯作者：
Feldman, Ruth