Impaired Feedback Processing for Symbolic Reward in Individuals with Internet Game Overuse.
Impaired Feedback Processing for Symbolic Reward in Individuals with Internet Game Overuse.
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DOI：
10.3389/fpsyt.2017.00195
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发表时间：
2017
影响因子：
4.7
通讯作者：
Kang E
中科院分区：
文献类型：
--
作者：
Kim J;Kim H;Kang E
奖励处理在适应性行为中起着关键作用，在成瘾障碍中会受损，成瘾障碍伴有大脑奖励回路的功能异常。网络游戏障碍与物质成瘾一样，被认为与奖励处理受损有关，但对于它如何影响学习知之甚少，尤其是当反馈由不太显著的激励事件传达时。在此，我们使用金钱（±500韩元）和符号（汉字“对”或“错”）奖励与惩罚，研究网络游戏过度使用（IGO）组的行为表现和与反馈相关的神经反应是否发生改变。利用功能性磁共振成像，在一项视觉运动关联任务中，比较了有IGO问题的年轻男性（IGO组，n = 18，平均年龄 = 22.2±2.0岁）和年龄匹配的对照组（对照组，n = 20，平均年龄 = 21.2±2.1岁）对这两种奖励/惩罚反馈的大脑反应，该任务是学习英文字母与四种反应之一之间的关联。对于金钱或符号惩罚，在惩罚后的错误反应调整以及对惩罚的大脑反应方面，两组均未发现差异。然而，IGO个体更有可能无法选择之前由符号（而非金钱）奖励强化的反应。对奖励进行的全脑双向方差分析显示，IGO组在对两种奖励类型做出反应时，吻侧前扣带回皮质/腹内侧前额叶皮质（vmPFC）的激活减少，这表明奖励处理受损。然而，IGO组顶下小叶区域和内侧眶额皮质/vmPFC对奖励的反应受奖励类型的影响。与对照组不同，在IGO组中，仅对符号奖励的奖励反应降低，这表明对符号奖励的注意力和价值处理较低。此外，IGO组中网络游戏过度使用症状越严重，相对于符号奖励，腹侧纹状体对金钱奖励的激活越强。这些发现表明，IGO与对具有激励显著性的奖励的偏向有关，这将导致日常生活中目标导向行为不良。
Reward processing, which plays a critical role in adaptive behavior, is impaired in addiction disorders, which are accompanied by functional abnormalities in brain reward circuits. Internet gaming disorder, like substance addiction, is thought to be associated with impaired reward processing, but little is known about how it affects learning, especially when feedback is conveyed by less-salient motivational events. Here, using both monetary (±500 KRW) and symbolic (Chinese characters “right” or “wrong”) rewards and penalties, we investigated whether behavioral performance and feedback-related neural responses are altered in Internet game overuse (IGO) group. Using functional MRI, brain responses for these two types of reward/penalty feedback were compared between young males with problems of IGO (IGOs, n = 18, mean age = 22.2 ± 2.0 years) and age-matched control subjects (Controls, n = 20, mean age = 21.2 ± 2.1) during a visuomotor association task where associations were learned between English letters and one of four responses. No group difference was found in adjustment of error responses following the penalty or in brain responses to penalty, for either monetary or symbolic penalties. The IGO individuals, however, were more likely to fail to choose the response previously reinforced by symbolic (but not monetary) reward. A whole brain two-way ANOVA analysis for reward revealed reduced activations in the IGO group in the rostral anterior cingulate cortex/ventromedial prefrontal cortex (vmPFC) in response to both reward types, suggesting impaired reward processing. However, the responses to reward in the inferior parietal region and medial orbitofrontal cortex/vmPFC were affected by the types of reward in the IGO group. Unlike the control group, in the IGO group the reward response was reduced only for symbolic reward, suggesting lower attentional and value processing specific to symbolic reward. Furthermore, the more severe the Internet gaming overuse symptoms in the IGO group, the greater the activations of the ventral striatum for monetary relative to symbolic reward. These findings suggest that IGO is associated with bias toward motivationally salient reward, which would lead to poor goal-directed behavior in everyday life.
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影响因子：
56.9
作者：
Hare, Todd A.;Camerer, Colin F.;Rangel, Antonio
通讯作者：
Rangel, Antonio
影响因子：
64.8
作者：
Flagel SB;Clark JJ;Robinson TE;Mayo L;Czuj A;Willuhn I;Akers CA;Clinton SM;Phillips PE;Akil H
通讯作者：
Akil H
DOI：
10.1089/cpb.2006.9956
发表时间：
2007-04-01
期刊：
CYBERPSYCHOLOGY & BEHAVIOR
影响因子：
--
作者：
Gruesser, S. M.;Thalemann, R.;Griffiths, M. D.
通讯作者：
Griffiths, M. D.
DOI：
10.1016/j.pnpbp.2013.07.007
发表时间：
2013-10-01
影响因子：
5.6
作者：
Dong, Guangheng;Hu, Yanbo;Lin, Xiao
通讯作者：
Lin, Xiao
影响因子：
3.9
作者：
Dong, Guangheng;Shen, Yue;Du, Xiaoxia
通讯作者：
Du, Xiaoxia