The Natural Products Atlas 2.0: a database of microbially-derived natural products.
The Natural Products Atlas 2.0: a database of microbially-derived natural products.
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天然产物图谱2.0:微生物衍生的天然产物数据库。
DOI:
10.1093/nar/gkab941
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发表时间:
2022-01-07
影响因子:
14.9
通讯作者:
Linington RG
中科院分区:
文献类型:
--
作者:
van Santen JA;Poynton EF;Iskakova D;McMann E;Alsup TA;Clark TN;Fergusson CH;Fewer DP;Hughes AH;McCadden CA;Parra J;Soldatou S;Rudolf JD;Janssen EM;Duncan KR;Linington RG
Within the natural products field there is an increasing emphasis on the study of compounds from microbial sources. This has been fuelled by interest in the central role that microorganisms play in mediating both interspecies interactions and host-microbe relationships. To support the study of natural products chemistry produced by microorganisms we released the Natural Products Atlas, a database of known microbial natural products structures, in 2019. This paper reports the release of a new version of the database which includes a full RESTful application programming interface (API), a new website framework, and an expanded database that includes 8128 new compounds, bringing the total to 32 552. In addition to these structural and content changes we have added full taxonomic descriptions for all microbial taxa and have added chemical ontology terms from both NP Classifier and ClassyFire. We have also performed manual curation to review all entries with incomplete configurational assignments and have integrated data from external resources, including CyanoMetDB. Finally, we have improved the user experience by updating the Overview dashboard and creating a dashboard for taxonomic origin. The database can be accessed via the new interactive website at https://www.npatlas.org.
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影响因子:
14.9
作者:
Davies M;Nowotka M;Papadatos G;Dedman N;Gaulton A;Atkinson F;Bellis L;Overington JP
通讯作者:
Overington JP
影响因子:
11.9
作者:
Rudolf JD;Alsup TA;Xu B;Li Z
通讯作者:
Li Z
影响因子:
8.6
作者:
Djoumbou Feunang Y;Eisner R;Knox C;Chepelev L;Hastings J;Owen G;Fahy E;Steinbeck C;Subramanian S;Bolton E;Greiner R;Wishart DS
通讯作者:
Wishart DS
影响因子:
8.6
作者:
Sorokina M;Merseburger P;Rajan K;Yirik MA;Steinbeck C
通讯作者:
Steinbeck C
DOI:
10.1099/ijsem.0.004332
发表时间:
2020-11
影响因子:
2.8
作者:
Parte AC;Sardà Carbasse J;Meier-Kolthoff JP;Reimer LC;Göker M
通讯作者:
Göker M