Early life stress and physical and psychosocial functioning in late adulthood.
Early life stress and physical and psychosocial functioning in late adulthood.
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DOI：
10.1371/journal.pone.0069011
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Eriksson JG
中科院分区：
文献类型：
--
作者：
Alastalo H;von Bonsdorff MB;Räikkönen K;Pesonen AK;Osmond C;Barker DJ;Heinonen K;Kajantie E;Eriksson JG
早年经历的严重压力可能对成年人的生理和心理健康和福祉产生长期影响。我们研究了第二次世界大战期间儿童时期暂时与父母分离的受试者在成年后期的身体和心理社会功能。1803名参与者属于赫尔辛基出生队列研究，出生于1934-44年。其中267人（14.8%）曾在二战期间被疏散到国外，其余的科目作为对照。在2001年至2004年期间，使用简明健康量表（SF-36）评估了身体和心理社会功能。趋势检验基于线性回归。所有的分析都调整了临床检查时的年龄，儿童和成人的社会阶层，吸烟，饮酒，体力活动，体重指数，心血管疾病和糖尿病。与未分居男性相比，分居男性成年后期的身体功能较低（B =-0.40，95%置信区间[95%CI]：-0.71至-0.08）。 那些在学龄时分离（>7年）和分离时间超过2年的男性身体功能低下的风险最高（分别为B=-0.89，95% CI：-1.58至0.20）和（B =-0.65，95% CI：-1.25至0.05）。 分离时间超过2年的男性的社会心理功能也较低（B =-0.70，95% CI：-1.35至-0.06）。 在妇女中没有观察到生理和心理社会功能方面的这些差异。早期生活压力可能会增加男性成年后期身体功能受损的风险。分离的时间和持续时间影响成年后期的身体和心理社会功能。
Severe stress experienced in early life may have long-term effects on adult physiological and psychological health and well-being. We studied physical and psychosocial functioning in late adulthood in subjects separated temporarily from their parents in childhood during World War II. The 1803 participants belong to the Helsinki Birth Cohort Study, born 1934–44. Of them, 267 (14.8%) had been evacuated abroad in childhood during WWII and the remaining subjects served as controls. Physical and psychosocial functioning was assessed with the Short Form 36 scale (SF-36) between 2001 and 2004. A test for trends was based on linear regression. All analyses were adjusted for age at clinical examination, social class in childhood and adulthood, smoking, alcohol intake, physical activity, body mass index, cardiovascular disease and diabetes. Physical functioning in late adulthood was lower among the separated men compared to non-separated men (b = −0.40, 95% confidence interval [95% CI]: −0.71 to −0.08). Those men separated in school age (>7 years) and who were separated for a duration over 2 years had the highest risk for lower physical functioning (b = −0.89, 95% CI: −1.58 to −0.20) and (b = −0.65, 95% CI: −1.25 to −0.05), respectively). Men separated for a duration over 2 years also had lower psychosocial functioning (b = −0.70, 95% CI: −1.35 to −0.06). These differences in physical and psychosocial functioning were not observed among women. Early life stress may increase the risk for impaired physical functioning in late adulthood among men. Timing and duration of the separation influenced the physical and psychosocial functioning in late adulthood.
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影响因子：
3.7
作者：
Lachman, Margie E.;Agrigoroaei, Stefan
通讯作者：
Agrigoroaei, Stefan
影响因子：
6.3
作者：
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通讯作者：
Parker, L
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作者：
Carpenter, Linda L.;Carvalho, John P.;Price, Lawrence H.
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Price, Lawrence H.
影响因子：
8.2
作者：
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影响因子：
158.5
作者：
Barker, DJP;Osmond, C;Eriksson, JG
通讯作者：
Eriksson, JG