Filariasis in travelers presenting to the GeoSentinel Surveillance Network.
Filariasis in travelers presenting to the GeoSentinel Surveillance Network.
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DOI：
10.1371/journal.pntd.0000088
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发表时间：
2007-12-26
影响因子：
3.8
通讯作者：
GeoSentinel Surveillance Network
中科院分区：
文献类型：
--
作者：
Lipner EM;Law MA;Barnett E;Keystone JS;von Sonnenburg F;Loutan L;Prevots DR;Klion AD;Nutman TB;GeoSentinel Surveillance Network
随着国际旅行的增加，人们越来越多地接触到世界上资源丰富的国家传统上没有遇到的许多病原体。丝虫感染是整个热带和亚热带地区的一个大问题，即使是前往世界上丝虫病流行地区的旅行者也相对罕见。GeoSentinel监测网络是一个全球医疗/旅行诊所网络，成立于1995年，目的是检测旅行者的发病趋势。我们检查了GeoSentinel数据库中的数据，以确定与丝虫病收购相关的人口统计学和旅行特征，并了解非流行游客和世界丝虫病流行地区出生的游客之间临床表现的差异。丝虫感染占旅行者向GeoSentinel网络报告的所有医疗状况的0.62%（n=271）; 37%的患者被诊断为盘尾丝虫，25%被感染Loa loa，另有25%被诊断为班氏吴策线虫。 据报告，大多数感染来自移民和返回原籍国的移民（探亲访友者）;大多数丝虫感染发生在撒哈拉以南非洲。在丝虫病非流行区的本地人中，70.6%的人感染丝虫病超过1个月。此外，与终身接触的人相比，丝虫病流行地区的非流行游客更有可能出现临床症状的GeoSentinel站点。对提交给GeoSentinel监测网络的丝虫感染进行编码，可以深入了解感染丝虫的外籍人士和来自流行地区的人之间的临床差异，并证明O.肠扭转感染可通过短期旅行获得。随着国际旅行的增加，人们接触许多传统上在世界资源丰富的国家不会遇到的病原体的机会也在增加。GeoSentinel监测网络是一个全球医疗/旅行诊所网络，成立于1995年，目的是检测旅行者的发病趋势。在1995年至2004年期间向GeoSentinel网络报告的43 722种疾病中，丝虫感染（引起盘尾丝虫病[河盲症]、淋巴丝虫病[如象皮病、水肿、鞘膜积液]和非洲眼虫病]的寄生虫感染）占0.62%（n =271）。 来自丝虫病流行地区的移民是最有可能感染丝虫病的群体;撒哈拉以南非洲是世界上大多数丝虫病感染的地区。与短期旅行相比，长期旅行（超过1个月）更可能与获得其中一种丝虫感染相关。
As international travel increases, there is rising exposure to many pathogens not traditionally encountered in the resource-rich countries of the world. Filarial infections, a great problem throughout the tropics and subtropics, are relatively rare among travelers even to filaria-endemic regions of the world. The GeoSentinel Surveillance Network, a global network of medicine/travel clinics, was established in 1995 to detect morbidity trends among travelers. We examined data from the GeoSentinel database to determine demographic and travel characteristics associated with filaria acquisition and to understand the differences in clinical presentation between nonendemic visitors and those born in filaria-endemic regions of the world. Filarial infections comprised 0.62% (n = 271) of all medical conditions reported to the GeoSentinel Network from travelers; 37% of patients were diagnosed with Onchocerca volvulus, 25% were infected with Loa loa, and another 25% were diagnosed with Wuchereria bancrofti. Most infections were reported from immigrants and from those immigrants returning to their county of origin (those visiting friends and relatives); the majority of filarial infections were acquired in sub-Saharan Africa. Among the patients who were natives of filaria-nonendemic regions, 70.6% acquired their filarial infection with exposure greater than 1 month. Moreover, nonendemic visitors to filaria-endemic regions were more likely to present to GeoSentinel sites with clinically symptomatic conditions compared with those who had lifelong exposure. Codifying the filarial infections presenting to the GeoSentinel Surveillance Network has provided insights into the clinical differences seen among filaria-infected expatriates and those from endemic regions and demonstrated that O. volvulus infection can be acquired with short-term travel. As international travel increases, there is rising exposure to many pathogens not traditionally encountered in the resource-rich countries of the world. The GeoSentinel Surveillance Network, a global network of medicine/travel clinics, was established in 1995 to detect morbidity trends among travelers. Filarial infections (parasitic worm infections that cause, among others, onchocerciasis [river blindness], lymphatic filariasis [e.g. elephantiasis, lymphedema, hydrocele] and loiasis [African eyeworm]) comprised 0.62% (n = 271) of the 43,722 medical conditions reported to the GeoSentinel Network between 1995 and 2004. Immigrants from filarial-endemic regions comprised the group most likely to have acquired a filarial infection; sub-Saharan Africa was the region of the world where the majority of filarial infections were acquired. Long-term travel (greater than 1 month) was more likely to be associated with acquisition of one of the filarial infections than shorter-term travel.
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影响因子：
2.4
作者：
Chun, YS;Chun, SI;Lee, MG
通讯作者：
Lee, MG
影响因子：
25.7
作者：
Freedman, DO;Kozarsky, PE;Cetron, MS
通讯作者：
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影响因子：
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作者：
KLION, AD;MASSOUGBODJI, A;NUTMAN, TB
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DOI：
10.1016/s0924-8579(02)00293-5
发表时间：
2003-02-01
影响因子：
10.8
作者：
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通讯作者：
Ba単os, A
影响因子：
158.5
作者：
Freedman, DO;Weld, LH;Cetron, MS
通讯作者：
Cetron, MS