Future directions: lung aging, inflammation, and human immunodeficiency virus.
Future directions: lung aging, inflammation, and human immunodeficiency virus.
复制标题
DOI：
10.1016/j.ccm.2013.01.010
复制
发表时间：
2013-06
影响因子：
5.7
通讯作者：
Morris A
中科院分区：
文献类型：
--
作者：
Fitzpatrick M;Crothers K;Morris A
Chronic lung diseases, including chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH) are unusually prevalent among persons infected with HIV. In many cases these disease states are identified at younger ages than would be expected in the general population. Recent epidemiologic, basic science, and cross-sectional clinical data have implicated immune dysfunction and cellular senescence as potential drivers of advanced presentations of age-related diseases in HIV-infected persons. This article describes how HIV-associated COPD and PH may fit into a paradigm of immunosenescence and outlines the hypothesized associations among chronic HIV infection, immune dysfunction and senescence, and cardiopulmonary outcomes.
登录
查看更多内容
影响因子：
4.6
作者：
Gingo, Matthew R.;Morris, Alison
通讯作者：
Morris, Alison
影响因子：
9.1
作者：
El Chami, Hala;Hassoun, Paul M.
通讯作者：
Hassoun, Paul M.
影响因子：
158.5
作者：
Bozzette, SA;Ake, CF;Louis, TA
通讯作者：
Louis, TA
影响因子：
2.9
作者：
Effros, RB
通讯作者：
Effros, RB
影响因子：
9.6
作者：
Crothers, Kristina;Butt, Adeel A.;Justice, Amy C.
通讯作者：
Justice, Amy C.