Stakeholders' Understandings of Human Papillomavirus (HPV) Vaccination in Sub-Saharan Africa: A Rapid Qualitative Systematic Review.

Stakeholders' Understandings of Human Papillomavirus (HPV) Vaccination in Sub-Saharan Africa: A Rapid Qualitative Systematic Review.
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DOI:
10.3390/vaccines9050496
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发表时间:
2021-05-12
期刊:
影响因子:
7.8
通讯作者:
Colvin CJ
Colvin CJ
中科院分区:
医学3区
文献类型:
--
作者:
Deignan C;Swartz A;Cooper S;Colvin CJ

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撒哈拉以南非洲(SSA)的宫颈癌发病率是世界上最高的。所有三种人乳头瘤病毒(HPV)疫苗(9价、四价和二价HPV疫苗)对最常见的致癌HPV毒株(16型和18型)提供初级保护,已知这些毒株导致70%的宫颈癌。在过去五年中,撒哈拉以南非洲国家引入HPV疫苗的人数有所增加。大多数研究都是关于供应方的障碍和促进人乳头瘤病毒疫苗接种的因素,但很少有研究从需求方或最终用户的角度以及围绕人乳头瘤病毒疫苗接种的决定进行的。为了补充现有的研究,并为当前和未来的HPV疫苗接种实施方法提供信息,本定性系统评价探讨了利益相关者对SSA中HPV疫苗接种的理解。本综述检索了以下数据库:Embase(通过Scopus)、Scopus、MEDLINE(通过PubMed)、PubMed、EBSCOhost、Academic Search Premier、Africa-Wide Information、CINAHL、PsycARTICLES、PsycINFO、SocINDEX、Web of Science和Cochrane Controlled Register of Trials (CENTRAL),共发现259篇文章。31项研究被发现符合纳入条件,并使用Braun和Clarke的方法进行主题分析。纳入研究的质量采用关键评估技能计划(CASP)检查表进行评估。这一分析产生了三个主要主题;关于HPV疫苗接种和宫颈癌的知识与错误信息交织在一起;恐惧形成了对HPV疫苗接种的矛盾看法,性别动态与利益相关者如何理解SSA的HPV疫苗接种有关。
Cervical cancer rates in Sub-Saharan Africa (SSA) are amongst the highest worldwide. All three of the Human Papillomavirus (HPV) vaccines (9-valent, quadrivalent and bivalent HPV vaccine) provide primary protection against the most common cancer-causing strains of HPV (types 16 and 18) that are known to cause 70% of cervical cancers. Over the last five years, there has been an increase in Sub-Saharan African countries that have introduced the HPV vaccine. The majority of research has been conducted on supply-side barriers and facilitators to HPV vaccination uptake in SSA, yet little research has been conducted on demand-side or end-user perspectives of, and decisions around, HPV vaccination. In order to complement existing research, and inform current and future HPV vaccination implementation approaches, this qualitative systematic review explored Stakeholders’ understandings of HPV vaccination in SSA. This review searched the following databases: Embase (via Scopus), Scopus, MEDLINE (via PubMed), PubMed, EBSCOhost, Academic Search Premier, Africa-Wide Information, CINAHL, PsycARTICLES, PsycINFO, SocINDEX, Web of Science, and the Cochrane Controlled Register of Trials (CENTRAL) and found a total of 259 articles. Thirty-one studies were found eligible for inclusion and were analyzed thematically using Braun and Clarke’s methods for conducting a thematic analysis. The quality of included studies was assessed using the Critical Appraisal Skills Programme (CASP) checklist. Three major themes emerged from this analysis; knowledge of HPV vaccination and cervical cancer is intertwined with misinformation; fear has shaped contradictory perceptions about HPV vaccination and gender dynamics are relevant in how stakeholders understand HPV vaccination in SSA.
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期刊: BMC PUBLIC HEALTH
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