A network for computing value homeostasis in the human medial prefrontal cortex

A network for computing value homeostasis in the human medial prefrontal cortex
复制标题

用于计算人类内侧前额叶皮层价值稳态的网络

DOI:
10.1101/278531
复制
发表时间:
2018
期刊:
--
影响因子:
--
通讯作者:
Juechems K
Juechems K
中科院分区:
--
文献类型:
--
作者:
Juechems K

文献摘要

参考文献

相似文献

人类和其他动物做出决定是为了实现他们的目标。然而,目前仍不清楚神经回路如何计算应该追求多个可能目标中的哪一个(例如,平衡饥饿和口渴时)以及如何将这些信号与可用奖励替代方案的估计相结合。在这里,接受功能磁共振成像的人类在一系列试验中积累了两种不同的资产。 财务结果取决于任一资产的最小累积,因此需要通过纠正资产之间的任何不平衡来维持“价值平衡”。头侧前扣带皮层 (rACC) 中的血氧水平依赖性 (BOLD) 信号追踪目标之间的不平衡水平,而腹内侧前额叶皮层 (vmPFC) 则表示因选择而产生的补救水平,而不是收到的总体金额。这些结果表明,内侧额叶脑区域网络计算出维持内部目标之间价值平衡的价值信号。
Humans and other animals make decisions in order to satisfy their goals. However, it remains unknown how neural circuits compute which of multiple possible goals should be pursued (e.g., when balancing hunger and thirst) and how to combine these signals with estimates of available reward alternatives. Here, humans undergoing fMRI accumulated two distinct assets over a sequence of trials. Financial outcomes depended on the minimum cumulate of either asset, creating a need to maintain "value equilibrium" by redressing any imbalance among the assets. Blood-oxygen-level-dependent (BOLD) signals in the rostral anterior cingulate cortex (rACC) tracked the level of imbalance among goals, whereas the ventromedial prefrontal cortex (vmPFC) signaled the level of redress incurred by a choice rather than the overall amount received. These results suggest that a network of medial frontal brain regions compute a value signal that maintains value equilibrium among internal goals.
稀缺性:缺乏的真正代价
DOI: --
发表时间: 2014
期刊:
影响因子: --
作者:
S. Mullainathan;E. Shafir
通讯作者: E. Shafir
DOI: 10.1038/s41467-018-02974-x
发表时间: 2018-02-05
影响因子: 16.6
作者:
Koch RE;Kavazis AN;Hasselquist D;Hood WR;Zhang Y;Toomey MB;Hill GE
通讯作者: Hill GE
DOI: 10.1016/j.neuroimage.2011.06.078
发表时间: 2011-09-15
期刊: NEUROIMAGE
影响因子: 5.7
作者:
Sladky, Ronald;Friston, Karl J.;Troestl, Jasmin;Cunnington, Ross;Moser, Ewald;Windischberger, Christian
通讯作者: Windischberger, Christian
DOI: 10.1016/j.neuron.2013.09.007
发表时间: 2013-10-16
期刊: Neuron
影响因子: 16.2
作者:
Dolan RJ;Dayan P
通讯作者: Dayan P
DOI: 10.7554/elife.03671
发表时间: 2014-07-20
期刊: eLife
影响因子: 7.7
作者:
Wang W;Whorton MR;MacKinnon R
通讯作者: MacKinnon R