A network for computing value homeostasis in the human medial prefrontal cortex
A network for computing value homeostasis in the human medial prefrontal cortex
复制标题
用于计算人类内侧前额叶皮层价值稳态的网络
DOI:
10.1101/278531
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Juechems K
中科院分区:
文献类型:
--
作者:
Juechems K
Humans and other animals make decisions in order to satisfy their goals. However, it remains unknown how neural circuits compute which of multiple possible goals should be pursued (e.g., when balancing hunger and thirst) and how to combine these signals with estimates of available reward alternatives. Here, humans undergoing fMRI accumulated two distinct assets over a sequence of trials. Financial outcomes depended on the minimum cumulate of either asset, creating a need to maintain "value equilibrium" by redressing any imbalance among the assets. Blood-oxygen-level-dependent (BOLD) signals in the rostral anterior cingulate cortex (rACC) tracked the level of imbalance among goals, whereas the ventromedial prefrontal cortex (vmPFC) signaled the level of redress incurred by a choice rather than the overall amount received. These results suggest that a network of medial frontal brain regions compute a value signal that maintains value equilibrium among internal goals.
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DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
S. Mullainathan;E. Shafir
通讯作者:
E. Shafir
影响因子:
16.6
作者:
Koch RE;Kavazis AN;Hasselquist D;Hood WR;Zhang Y;Toomey MB;Hill GE
通讯作者:
Hill GE
影响因子:
5.7
作者:
Sladky, Ronald;Friston, Karl J.;Troestl, Jasmin;Cunnington, Ross;Moser, Ewald;Windischberger, Christian
通讯作者:
Windischberger, Christian
影响因子:
16.2
作者:
Dolan RJ;Dayan P
通讯作者:
Dayan P
影响因子:
7.7
作者:
Wang W;Whorton MR;MacKinnon R
通讯作者:
MacKinnon R