Cytoskeleton responses in wound repair.
Cytoskeleton responses in wound repair.
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DOI：
10.1007/s00018-012-0928-2
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发表时间：
2012-08
影响因子：
8
通讯作者：
Parkhurst, Susan M.
中科院分区：
文献类型：
--
作者：
Abreu-Blanco, Maria Teresa;Watts, James J.;Verboon, Jeffrey M.;Parkhurst, Susan M.
Wound repair on the cellular and multicellular levels is essential to the survival of complex organisms. In order to avoid further damage, prevent infection, and restore normal function, cells and tissues must rapidly seal and remodel the wounded area. The cytoskeleton is an important component of wound repair, needed for actomyosin contraction, recruitment of repair machineries, and cell migration. Recent use of model systems and high-resolution microscopy has provided new insight into molecular aspects of the cytoskeletal response during wound repair. Here we discuss the role of the cytoskeleton in single cell, embryonic, and adult repair, as well as the striking resemblance of these processes to normal developmental events and many diseases.
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DOI：
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发表时间：
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期刊：
Current biology : CB
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