Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021.

Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021.
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DOI:
10.3390/v15010016
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发表时间:
2022-12-21
期刊:
Viruses
影响因子:
--
通讯作者:
--
中科院分区:
其他
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动物流行性出血症(EHD)是由动物流行性出血症病毒(EHDV)引起的库蠓传播的病毒性疾病,与家养和野生反刍动物的临床表现相关,主要是白尾鹿(Odocoileus virginianus)和牛(Bos taurus)。2021年9月下旬,突尼斯中部/西部的养牛场报告了EHDV。它迅速蔓延到全国各地,有200多起确诊疫情。我们应用经典和分子技术相结合的特点,致病病毒的血清型EHDV-8的成员。这是自1982年在澳大利亚分离出EHDV-8原型菌株以来,EHDV- 8循环的第一个证据。这项工作强调了对一系列EHDV血清型疫苗的迫切需要。
Epizootic haemorrhagic disease (EHD) is a Culicoides-borne viral disease caused by the epizootic haemorrhagic disease virus (EHDV) associated with clinical manifestations in domestic and wild ruminants, primarily white-tailed deer (Odocoileus virginianus) and cattle (Bos taurus). In late September 2021, EHDV was reported in cattle farms in central/western Tunisia. It rapidly spread throughout the country with more than 200 confirmed outbreaks. We applied a combination of classical and molecular techniques to characterize the causative virus as a member of the serotype EHDV-8. This is the first evidence of EHDV- 8 circulation since 1982 when the prototype EHDV-8 strain was isolated in Australia. This work highlights the urgent need for vaccines for a range of EHDV serotypes.
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