BrainTrap: a database of 3D protein expression patterns in the Drosophila brain.

BrainTrap: a database of 3D protein expression patterns in the Drosophila brain.
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DOI:
10.1093/database/baq005
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发表时间:
2010-07-06
期刊:
Database : the journal of biological databases and curation
影响因子:
--
通讯作者:
Armstrong JD
Armstrong JD
中科院分区:
其他
文献类型:
--
作者:
Knowles-Barley S;Longair M;Armstrong JD

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果蝇的蛋白质捕获菌株为检查蛋白质的 3D 表达模式和纯化蛋白质复合物提供了非常有用的工具。在这里,我们介绍 BrainTrap,可在 http://fruitfly.inf.ed.ac.uk/braintrap 上获得,这是一个 3D 共聚焦数据集的在线数据库,显示果蝇成年大脑中的报告基因表达和蛋白质定位。整个大脑的全尺寸图像可以在网络浏览器中交互式地查看。该数据库包括与 FlyBase 果蝇解剖本体相关的可搜索注释。可以使用自动完成和本体的分层浏览器来指定解剖搜索标准。所有注释的出处都会被保留,并且注释者得出结论的位置可以突出显示。数据库网址:http://fruitfly.inf.ed.ac.uk/braintrap
Protein-trap strains of Drosophila melanogaster provide a very useful tool for examining the 3D-expression patterns of proteins and purification of protein complexes. Here we present BrainTrap, available at http://fruitfly.inf.ed.ac.uk/braintrap, an online database of 3D confocal datasets showing reporter gene expression and protein localization in the adult brain of Drosophila. Full size images throughout the volume of the entire brain can be viewed interactively in a web browser. The database includes searchable annotations linked to the FlyBase Drosophila anatomy ontology. Anatomical search criteria can be specified using automatic completion and a hierarchical browser for the ontology. The provenance of all annotation is retained and the location where the annotator made the conclusion can be highlighted. Database URL: http://fruitfly.inf.ed.ac.uk/braintrap
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发表时间: 2006-01-01
影响因子: 14.9
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