Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan.

Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan.
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DOI:
10.1186/1471-2334-11-111
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发表时间:
2011-05-03
影响因子:
3.7
通讯作者:
Kamiya K
Kamiya K
中科院分区:
医学3区
文献类型:
--
作者:
Nishiura H;Kamiya K

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入境检查往往从寻找发热的国际乘客开始,日本已采用红外热扫描仪进行发热检查。我们的目的是回顾性地评估基于发热筛查作为唯一措施检测流感病例的可行性。在2009年大流行期间,在成田国际机场收集了两个数据集。第一个包含确诊的流感病例(n = 16),其诊断是在大流行的早期阶段在机场进行的,第二个包含2009年9月至2010年1月筛选的选定和疑似部分乘客(自我报告或通过红外热扫描仪检测; n = 1,049)。估计了发热(38.0°C)检测H1N1-2009的灵敏度,还估计了红外热扫描仪在检测37.5°C、38.0°C和38.5°C临界水平下的高热的诊断性能。在9例确诊的H1N1-2009病例中,发热对抵达时检测H1N1 - 2009病例的敏感性估计为22.2%(95%置信区间:0.55.6),55.6%的H1N1-2009病例在抵达时正在服用退热药物。红外热扫描仪检测体温过高的敏感性和特异性分别为50.8-70.4%和63.6- 81.7%。阳性预测值似乎低至37.3- 68.0%。入境检查的灵敏度是发热对检测流感病例的灵敏度和红外热扫描仪检测发热的灵敏度的乘积。鉴于旅客中存在其他混杂因素和不受限制的药物,仅依靠发烧作为入境筛查措施不太可能可行。
Entry screening tends to start with a search for febrile international passengers, and infrared thermoscanners have been employed for fever screening in Japan. We aimed to retrospectively assess the feasibility of detecting influenza cases based on fever screening as a sole measure. Two datasets were collected at Narita International Airport during the 2009 pandemic. The first contained confirmed influenza cases (n = 16) whose diagnosis took place at the airport during the early stages of the pandemic, and the second contained a selected and suspected fraction of passengers (self-reported or detected by an infrared thermoscanner; n = 1,049) screened from September 2009 to January 2010. The sensitivity of fever (38.0°C) for detecting H1N1-2009 was estimated, and the diagnostic performances of the infrared thermoscanners in detecting hyperthermia at cut-off levels of 37.5°C, 38.0°C and 38.5°C were also estimated. The sensitivity of fever for detecting H1N1-2009 cases upon arrival was estimated to be 22.2% (95% confidence interval: 0, 55.6) among nine confirmed H1N1-2009 cases, and 55.6% of the H1N1-2009 cases were under antipyretic medications upon arrival. The sensitivity and specificity of the infrared thermoscanners in detecting hyperthermia ranged from 50.8-70.4% and 63.6-81.7%, respectively. The positive predictive value appeared to be as low as 37.3-68.0%. The sensitivity of entry screening is a product of the sensitivity of fever for detecting influenza cases and the sensitivity of the infrared thermoscanners in detecting fever. Given the additional presence of confounding factors and unrestricted medications among passengers, reliance on fever alone is unlikely to be feasible as an entry screening measure.
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发表时间: 2010-04
期刊: The Journal of infection
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DOI: 10.1016/j.mvr.2004.05.003
发表时间: 2004-09-01
影响因子: 3.1
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Ng, EYK;Kaw, GJL;Chang, WM
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