A parallel imaging approach to wide-field MR microscopy.

A parallel imaging approach to wide-field MR microscopy.
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DOI:
10.1002/mrm.23258
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发表时间:
2012-09
影响因子:
3.3
通讯作者:
Wright, Steven M.
Wright, Steven M.
中科院分区:
医学3区
文献类型:
--
作者:
McDougall, Mary Preston;Wright, Steven M.

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磁共振显微镜(MRM),建议在最早的论文中的MRI,一直受到限制的低信噪比(SNR)所造成的小体素的大小。MRM在很大程度上是通过使用微弹簧圈实现的,微弹簧圈提供了克服这一限制所需的SNR改善。伴随小线圈的是小视场,这限制了MRM作为组织学工具或一般用于大区域成像的使用。本文介绍了在宽视场MR显微镜使用一个大的阵列的狭窄,平行线圈,它提供了一个SNR增强以及使用并行成像技术的能力的初步结果。体积线圈和所提出的技术之间的比较图像表明,在SNR或分辨率没有损失的情况下,成像时间减少超过100。
Magnetic resonance microscopy (MRM), suggested in the earliest papers on MRI, has always been limited by the low signal-to-noise ratio (SNR) resulting from the small voxel size. MRM has largely been enabled by the use of microcoils which provide the SNR improvement required to overcome this limitation. Concomitant with the small coils is a small field-of-view, which limits the use of MRM as a histological tool or for imaging large regions in general. This paper describes initial results in wide field-of-view MR microscopy using a large array of narrow, parallel coils, which provides an SNR enhancement as well as the ability to use parallel imaging techniques. Comparison images made between a volume coil and the proposed technique demonstrate reductions in imaging time of over 100 with no loss in SNR or resolution.
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期刊: NATURE
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