Robust and task-independent spatial profile of the visual word form activation in fusiform cortex.
Robust and task-independent spatial profile of the visual word form activation in fusiform cortex.
复制标题
梭形皮层视觉词形激活的鲁棒且与任务无关的空间分布
DOI：
10.1371/journal.pone.0026310
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Weng X
中科院分区：
文献类型：
--
作者：
Ma L;Jiang Y;Bai J;Gong Q;Liu H;Chen HC;He S;Weng X
书面语言是一类特殊的视觉信息。有强有力的证据表明，腹侧枕颞叶皮层中存在一个处理书面文字视觉形式的皮层区域。然而，由于不同的任务获得的结果不一致，这个所谓的视觉词形区（VWFA）的专业化水平和选择性仍然存在争议。本研究考察了汉语本族语读者对汉字（一种非拼音文字）的类别选择性。与传统的在有限的预定义感兴趣区域（ROI）检查反应水平的方法相比，BOLD信号在中梭状皮质表面的详细分布和对汉字的反应的空间模式被获得。结果表明，汉语阅读者在左梭状回外侧部存在一个与汉字相关的区域，这种对汉字选择性的空间模式不受语音或语义等自上而下任务的影响。这些结果提供了强有力的支持，在中间梭状皮质的类别选择性反应的强大的空间编码，并证明了实用程序的空间分布分析作为一个更有意义的方法来检查功能磁共振成像（fMRI）的数据。
Written language represents a special category of visual information. There is strong evidence for the existence of a cortical region in ventral occipitotemporal cortex for processing the visual form of written words. However, due to inconsistent findings obtained with different tasks, the level of specialization and selectivity of this so called visual word form area (VWFA) remains debated. In this study, we examined category selectivity for Chinese characters, a non-alphabetic script, in native Chinese readers. In contrast to traditional approaches of examining response levels in a restricted predefined region of interest (ROI), a detailed distribution of the BOLD signal across the mid-fusiform cortical surface and the spatial patterns of responses to Chinese characters were obtained. Results show that a region tuned for Chinese characters could be consistently found in the lateral part of the left fusiform gyrus in Chinese readers, and this spatial pattern of selectivity for written words was not influenced by top-down tasks such as phonological or semantic modulations. These results provide strong support for the robust spatial coding of category selective response in the mid-fusiform cortex, and demonstrate the utility of the spatial distribution analysis as a more meaningful approach to examine functional magnetic resonance imaging (fMRI) data.
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DOI：
10.1093/cercor/bhq063
发表时间：
2011-01
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Kherif F;Josse G;Price CJ
通讯作者：
Price CJ
影响因子：
3.2
作者：
Devlin, Joseph T.;Jamison, Helen L.;Gonnerman, Laura M.;Matthews, Paul M.
通讯作者：
Matthews, Paul M.
影响因子：
9.2
作者：
Reich, Lior;Szwed, Marcin;Amedi, Amir
通讯作者：
Amedi, Amir
影响因子：
5.3
作者：
Woodhead, Zoe V. J.;Brownsett, Sonia L. E.;Wise, Richard J. S.
通讯作者：
Wise, Richard J. S.
影响因子：
3.2
作者：
Cai, Qing;Lavidor, Michal;Nazir, Tatjana A.
通讯作者：
Nazir, Tatjana A.