Population genomic analysis of the rice blast fungus reveals specific events associated with expansion of three main clades.
Population genomic analysis of the rice blast fungus reveals specific events associated with expansion of three main clades.
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稻瘟病菌的群体基因组分析揭示了与三个主要分支扩张相关的特定事件
DOI：
10.1038/s41396-018-0100-6
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发表时间：
2018-08
期刊：
影响因子：
--
通讯作者：
Wang Z
中科院分区：
文献类型：
--
作者：
Zhong Z;Chen M;Lin L;Han Y;Bao J;Tang W;Lin L;Lin Y;Somai R;Lu L;Zhang W;Chen J;Hong Y;Chen X;Wang B;Shen WC;Lu G;Norvienyeku J;Ebbole DJ;Wang Z
We examined the genomes of 100 isolates of Magnaporthe oryzae (Pyricularia oryzae), the causal agent of rice blast disease. We grouped current field populations of M. oryzae into three major globally distributed groups. A genetically diverse group, clade 1, which may represent a group of closely related lineages, contains isolates of both mating types. Two well-separated clades, clades 2 and 3, appear to have arisen as clonal lineages distinct from the genetically diverse clade. Examination of genes involved in mating pathways identified clade-specific diversification of several genes with orthologs involved in mating behavior in other fungi. All isolates within each clonal lineage are of the same mating type. Clade 2 is distinguished by a unique deletion allele of a gene encoding a small cysteine-rich protein that we determined to be a virulence factor. Clade 3 isolates have a small deletion within the MFA2 pheromone precursor gene, and this allele is shared with an unusual group of isolates we placed within clade 1 that contain AVR1-CO39 alleles. These markers could be used for rapid screening of isolates and suggest specific events in evolution that shaped these populations. Our findings are consistent with the view that M. oryzae populations in Asia generate diversity through recombination and may have served as the source of the clades 2 and 3 isolates that comprise a large fraction of the global population.
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影响因子：
5.8
作者：
Bradbury, Peter J.;Zhang, Zhiwu;Buckler, Edward S.
通讯作者：
Buckler, Edward S.
使用下一代 DNA 测序数据进行变异发现和基因分型的框架。
影响因子：
30.8
作者：
通讯作者：
--
影响因子：
12.3
作者：
Haas, Brian J.;Salzberg, Steven L.;Zhu, Wei;Pertea, Mihaela;Allen, Jonathan E.;Orvis, Joshua;White, Owen;Buell, C. Robin;Wortman, Jennifer R.
通讯作者：
Wortman, Jennifer R.
影响因子：
3.3
作者：
Chiapello H;Mallet L;Guérin C;Aguileta G;Amselem J;Kroj T;Ortega-Abboud E;Lebrun MH;Henrissat B;Gendrault A;Rodolphe F;Tharreau D;Fournier E
通讯作者：
Fournier E
DOI：
10.1109/tcbb.2013.133
发表时间：
2014-01-01
影响因子：
4.5
作者：
Guo, Jing;Jain, Ritika;Zheng, Jie
通讯作者：
Zheng, Jie